Elwany S, Mekhamer A
Br J Anaesth. 1987 Jun;59(6):755-9. doi: 10.1093/bja/59.6.755.
Forty patients were studied to investigate the effect of nasotracheal intubation on nasal mucociliary clearance measured with the radiopaque disc method under standard conditions. Postoperative mucociliary slowing on the intubated side was observed in 65% of patients. Difficult or prolonged intubation increased the incidence of mucociliary stasis. Age, sex, smoking history, tube size and the use of lubricants had no effect. Postoperative slowing of the clearance rate was most probably the result of mechanical trauma to the superficial epithelial layers, and recovery of function was reasonably rapid with conservative management.
对40名患者进行了研究,以调查在标准条件下采用不透X光线片法测量经鼻气管插管对鼻黏膜纤毛清除功能的影响。65%的患者在插管侧出现术后黏膜纤毛运动减慢。困难插管或长时间插管会增加黏膜纤毛淤滞的发生率。年龄、性别、吸烟史、导管尺寸和润滑剂的使用对此没有影响。术后清除率减慢很可能是表层上皮机械性损伤的结果,保守治疗后功能恢复相当迅速。