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智能互联设备在即时分子诊断中的应用:它们在应对 COVID-19 方面可以发挥什么作用?

Smart and connected devices in point-of-care molecular diagnostics: what role can they play in the response to COVID-19?

机构信息

Pediatric Infectious Diseases, Unity Point Health at St. Luke's Regional Medical Center, Iowa, United States.

Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa, United States.

出版信息

Expert Rev Mol Diagn. 2022 Aug;22(8):775-781. doi: 10.1080/14737159.2022.2122711. Epub 2022 Sep 11.

DOI:10.1080/14737159.2022.2122711
PMID:36069357
Abstract

INTRODUCTION

Coronavirus disease-2019 (COVID-19) has been a huge public health challenge that has led to significant morbidity and mortality across the globe. Given the high prevalence and continued circulation of SARS-CoV-2 infection globally, accurate and rapid point-of-care testing is critical.

AREAS COVERED

Knowledge of role of digital technology including smart and connected devices in rapid diagnosis of COVID-19 is an evolving area of scientific investigation. This review discusses the importance of rapid at-home point-of-care testing, highlighting the possible role of smart and connected device-based molecular diagnostics for COVID-19.

EXPERT OPINION

Accurate and rapid diagnostic modalities have the potential to improve accessibility and efficiency of diagnosis of symptomatic and asymptomatic patients and could be instrumental in timely implementation of appropriate therapeutic interventions as well as public health measures to mitigate spread of infection. With emerging challenges like newer viral variants, global vaccine shortages and vaccine hesitancy, accurate diagnostic testing with the ability to rapidly identify infection remains critical. Digital technologies are likely to become important tools in future of healthcare and technological advancements may play a crucial role in response to COVID-19 with the goal of ultimately overcoming this pandemic.

摘要

简介

2019 年冠状病毒病(COVID-19)是一项巨大的公共卫生挑战,在全球范围内导致了大量的发病率和死亡率。鉴于 SARS-CoV-2 感染在全球的高流行率和持续传播,准确和快速的即时护理检测至关重要。

涵盖领域

数字技术(包括智能和互联设备)在 COVID-19 快速诊断中的作用的知识是科学研究的一个不断发展的领域。这篇综述讨论了快速家庭即时护理检测的重要性,强调了基于智能和互联设备的分子诊断在 COVID-19 中的可能作用。

专家意见

准确和快速的诊断方式有可能提高有症状和无症状患者诊断的可及性和效率,并有助于及时实施适当的治疗干预措施以及公共卫生措施来减轻感染的传播。随着新的病毒变体、全球疫苗短缺和疫苗犹豫等新出现的挑战,能够快速识别感染的准确诊断检测仍然至关重要。数字技术可能成为未来医疗保健的重要工具,技术进步可能在应对 COVID-19 方面发挥关键作用,最终目标是克服这一大流行病。

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