Department of Obstetrics and Gynecology and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, SWEDEN.
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, SWEDEN.
Med Sci Sports Exerc. 2022 Dec 1;54(12):2054-2063. doi: 10.1249/MSS.0000000000002996. Epub 2022 Sep 3.
The aim of this study was to examine the cross-sectional and longitudinal associations of 24-h movement behaviors (sleep, sedentary behavior (SB), light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)) with body composition and cardiometabolic health in i) early and ii) late pregnancy (gestational weeks 14 and 37).
This observational study utilized cross-sectional ( n = 273) and longitudinal data ( n = 242) from the HealthyMoms trial. Time spent in movement behaviors over seven consecutive 24-h periods (ActiGraph wGT3x-BT accelerometer), body composition (Bod Pod), and cardiometabolic health indicators (glucose levels, homeostatic model for insulin resistance (HOMA-IR), systolic and diastolic blood pressure, metabolic syndrome (MetS) score) were measured in early and late pregnancy.
In early pregnancy, reallocating time to MVPA from LPA, SB, and sleep was associated with lower MetS score (adjusted γ = -0.343, P = 0.002). Correspondingly, reallocating time to LPA from SB and sleep in early pregnancy was associated with lower body weight (adjusted γ = -5.959, P = 0.047) and HOMA-IR (adjusted γ = -0.557, P = 0.031) at the same time point. Furthermore, reallocating time to LPA from SB and sleep in early pregnancy was associated with lower fat mass index (adjusted γ = -0.668, P = 0.028), glucose levels (adjusted γ = -0.315, P = 0.006), HOMA-IR (adjusted γ = -0.779, P = 0.004), and MetS score (adjusted γ = -0.470, P = 0.027) in late pregnancy. The changes in behaviors throughout pregnancy were not associated with body weight, body composition, and MetS score in late pregnancy.
Our results demonstrated that increasing LPA or MVPA while reducing SB and sleep was associated with lower weight and more favorable cardiometabolic health in early pregnancy. In contrast, LPA in early pregnancy seems to be a stimulus of enough intensity to improve body composition and cardiometabolic health indicators in late pregnancy.
本研究旨在探讨 24 小时运动行为（睡眠、久坐行为（SB）、低强度身体活动（LPA）和中高强度身体活动（MVPA））与早期和晚期妊娠（妊娠 14 周和 37 周）时身体成分和心血管代谢健康的横断面和纵向关联。
本观察性研究利用了 HealthyMoms 试验的横断面（n=273）和纵向数据（n=242）。在早期和晚期妊娠期间，通过 ActiGraph wGT3x-BT 加速度计测量 7 个连续 24 小时期间的运动行为时间，通过 Bod Pod 测量身体成分，通过血糖水平、稳态模型评估的胰岛素抵抗（HOMA-IR）、收缩压和舒张压、代谢综合征（MetS）评分等指标测量心血管代谢健康状况。
在早期妊娠中，将时间重新分配到 MVPA 中，减少 LPA、SB 和睡眠的时间与 MetS 评分降低相关（调整后γ=-0.343，P=0.002）。相应地，在早期妊娠中，将时间从 SB 和睡眠重新分配到 LPA 与同时点的体重（调整后γ=-5.959，P=0.047）和 HOMA-IR（调整后γ=-0.557，P=0.031）降低相关。此外，在早期妊娠中，将时间从 SB 和睡眠重新分配到 LPA 与脂肪质量指数（调整后γ=-0.668，P=0.028）、血糖水平（调整后γ=-0.315，P=0.006）、HOMA-IR（调整后γ=-0.779，P=0.004）和 MetS 评分（调整后γ=-0.470，P=0.027）降低相关。整个孕期行为的变化与晚期妊娠时的体重、身体成分和 MetS 评分无关。
我们的研究结果表明，在早期妊娠中，增加 LPA 或 MVPA，同时减少 SB 和睡眠，与体重降低和心血管代谢健康状况改善相关。相比之下，早期妊娠时的 LPA 似乎是一种足够强度的刺激，能够改善晚期妊娠时的身体成分和心血管代谢健康指标。
