National Institute of Children's Tuberculosis and Respiratory Diseases, Dolny Smokovec, Slovakia.
Clinic of Internal Medicine - Gastroenterology, Jessenius Faculty of Medicine in Martin (JFM CU), JFM CU, Comenius University in Bratislava, Kollárova 2, Martin, 036 01, Slovakia.
Indian J Pediatr. 2024 Feb;91(2):131-136. doi: 10.1007/s12098-022-04347-1. Epub 2022 Sep 7.
To develop a novel formula for pH probe placement with adequate accuracy.
Children (3-18 y) undergoing pH-metry were prospectively evaluated. Their height and corrected pH probe position under X-ray (2 vertebrae above the diaphragm) was recorded and the linear-regression analysis was performed to derive a novel formula. Its accuracy was checked on an additional group of prospectively included children. The success rate of a newly developed formula was estimated and compared to the performance of previously used formulae. The difference in the suggested placement of the probe (cm from nostrils) was calculated.
Based on 670 children with pH probe placed under X-ray, the following formula was developed using the linear-regression analysis: L = 0.184x + 4.4 (cm) (L = probe placement depth, x = body height). Its accuracy was confirmed on additional 111 children resulting in almost 85% success rate. The formula showed significant difference in the suggested placement from formulae used previously: +4.9 ± 0.8 cm, +2.4 ± 0.1 cm, +0.7 ± 0.6 cm, +1.1 ± 0.4 cm, +1.8 ± 0.3 cm, +2.2 ± 0.5 cm from the one by the Strobel, Moreau, Wilson, Nowak, Staiano-Clouse formulae, and the GOSH table with the calculated success rates of 1.8%, 43.2%, 65.8%, 77.5%, 65.8% and 54.1%, respectively. A table suggesting placement depth based on the body height was developed.
The present formula provides 85% success of pH probe placement in children ≥ 3 y suggesting its use in routine practice. More data are needed to confirm that probe adjustment under X-ray is unnecessary.
开发一种新的 pH 探头定位公式，以达到足够的准确性。
前瞻性评估接受 pH 测量的儿童（3-18 岁）。记录他们的身高和 X 线下校正后的 pH 探头位置（膈肌上方 2 个椎体），并进行线性回归分析，得出一个新的公式。在另一组前瞻性纳入的儿童中检查其准确性。估计新公式的成功率，并与之前使用的公式进行比较。计算探头（从鼻孔）建议放置位置的差异。
基于 670 名在 X 线下放置 pH 探头的儿童，使用线性回归分析得出以下公式：L=0.184x+4.4（cm）（L=探头放置深度，x=身高）。在另外 111 名儿童中验证其准确性，成功率接近 85%。该公式在建议的放置位置上与之前使用的公式有显著差异：+4.9±0.8cm、+2.4±0.1cm、+0.7±0.6cm、+1.1±0.4cm、+1.8±0.3cm、+2.2±0.5cm，分别来自 Strobel、Moreau、Wilson、Nowak、Staiano-Clouse 公式和 GOSH 表，相应的计算成功率为 1.8%、43.2%、65.8%、77.5%、65.8%和 54.1%。制定了一个基于身高建议放置深度的表格。
本公式在≥3 岁的儿童中 pH 探头定位成功率为 85%，建议在常规实践中使用。需要更多的数据来证实无需在 X 线下调整探头。
