Department of Veterinary Internal Medicine, Graduate School of Agricultural and Sciences, The University of Tokyo, Tokyo, Japan.
Veterinary Medical Center, Graduate School of Agricultural and Sciences, The University of Tokyo, Tokyo, Japan.
J Vet Med Sci. 2022 Nov 1;84(11):1465-1468. doi: 10.1292/jvms.22-0126. Epub 2022 Sep 8.
The associations of diet compositions with mucin secretion in gallbladder have not been investigated in dogs. This study aimed to examine the effects of a low-carbohydrate diet (LC) and a low-fat diet (LF) on bile mucin concentration and composition of gallbladder bile in six clinically healthy beagle dogs. After feeding of both diets, the bile mucin concentration was significantly decreased. In addition, there were significant decreases in the concentrations of taurochenodeoxycholic acid in bile, which is considered to promote mucin secretion, after feeding of both diets. The present study suggested that the proportions of carbohydrate and fat in diet affect the composition of gallbladder bile in dogs.
在狗中，饮食成分与胆囊粘液分泌的关系尚未得到研究。本研究旨在研究低碳水化合物饮食（LC）和低脂肪饮食（LF）对 6 只临床健康比格犬胆汁粘液浓度和组成的影响。喂养两种饮食后，胆汁粘液浓度显著降低。此外，喂养两种饮食后，被认为促进粘液分泌的牛磺鹅脱氧胆酸在胆汁中的浓度也显著降低。本研究表明，饮食中碳水化合物和脂肪的比例影响狗胆囊胆汁的组成。
