Flores C A, Wells M A, Morrill M, Bustamante S A, Koldovsky O
Department of Pediatrics, University of Arizona College of Medicine, Tucson 85724.
Nutrition. 1992 Nov-Dec;8(6):418-20.
Total bile acid concentrations in gallbladder bile and duodenal juice of neonatal piglets receiving sow milk were compared to values from 10-wk-old pigs receiving either high-fat low-carbohydrate (HF/LC) or low-fat high-carbohydrate (LF/HC) diets. Ten-week-old pigs on either diet had higher bile acid concentrations in gallbladder bile than newborn pigs (108.6 +/- 2.5 and 109.3 +/- 1.4 vs. 50.0 +/- 10.0 mM, mean +/- SE for HF/LC, LF/HC, and newborn, respectively, p < 0.007; n = 8-10). Ten-week-old pigs in the LF/HC group had higher bile acid concentrations in duodenal juice than either the HF/LC or newborn animals (31.7 +/- 4.2 vs. 16.8 +/- 2.5 and 14.7 +/- 1.8 mM, respectively, p < 0.0001). These data demonstrate that like the human neonate, the newborn pig has decreased bile acid concentrations available for digestion compared with the adult and resembles the adult pig adapted to a high-fat diet.
将接受母乳的新生仔猪胆囊胆汁和十二指肠液中的总胆汁酸浓度，与接受高脂肪低碳水化合物（HF/LC）或低脂肪高碳水化合物（LF/HC）饮食的10周龄猪的相应值进行了比较。两种饮食的10周龄猪胆囊胆汁中的胆汁酸浓度均高于新生仔猪（HF/LC、LF/HC和新生仔猪的平均值±标准误分别为108.6±2.5、109.3±1.4和50.0±10.0 mM，p<0.007；n = 8 - 10）。LF/HC组的10周龄猪十二指肠液中的胆汁酸浓度高于HF/LC组或新生动物（分别为31.7±4.2、16.8±2.5和14.7±1.8 mM，p<0.0001）。这些数据表明，与人类新生儿一样，新生仔猪与成年猪相比，可用于消化的胆汁酸浓度降低，并且类似于适应高脂肪饮食的成年猪。
