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肺癌合并复发性多软骨炎。

Lung Cancer Complicated by Relapsing Polychondritis.

机构信息

Department of Respiratory Medicine, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives, Japan.

Department of Radiation Oncology, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives, Japan.

出版信息

Intern Med. 2023 Apr 1;62(7):1049-1054. doi: 10.2169/internalmedicine.0203-22. Epub 2022 Sep 6.

Abstract

A 77-year-old man presented with a 1-month history of cough, pharyngeal discomfort, and weight loss. Chest radiography revealed a mass shadow in the right upper lung field. Bronchoscopy showed multiple white nodules along the tracheal cartilage ring. Although adenocarcinoma cells were detected in the mass, several biopsy specimens of the tracheal lesions exhibited no malignancy. F-fluorodeoxyglucose positron emission tomography revealed an intense accumulation in the mass, nasal septum, and tracheal cartilage. Furthermore, anti-type II collagen antibody levels were elevated. We finally diagnosed him with lung cancer complicated by relapsing polychondritis. Treatment with oral prednisolone was initiated, followed by sequential chemoradiotherapy for lung cancer.

摘要

一位 77 岁男性因咳嗽、咽部不适和体重减轻而就诊。胸部 X 线摄影显示右上肺野有一个肿块阴影。支气管镜检查显示气管软骨环上有多个白色小结节。尽管肿块中检测到腺癌细胞,但气管病变的几个活检标本均未见恶性肿瘤。氟代脱氧葡萄糖正电子发射断层扫描显示肿块、鼻中隔和气管软骨有强烈的积聚。此外,抗 II 型胶原抗体水平升高。我们最终诊断他患有肺癌合并复发性多软骨炎。开始口服泼尼松龙治疗,随后对肺癌进行序贯化疗和放疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3525/10125820/ff81ae9c956d/1349-7235-62-1049-g001.jpg

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