Invasive Growth of Trees is Associated with a High Rate of Sensitization in Atopic Patients.

PURPOSE

is one of the world's most invasive species with a globally problematic spread. Pollen is dispersed locally and partially airborne. We aimed at investigating if (i) pollen can be detected in relevant quantity in the air and if (ii) sensitization to can be detected in patients with seasonal exacerbation of atopic diseases.

PATIENTS AND METHODS

We recorded distribution of in Leipzig, Germany. In 2019 and 2020, pollen was collected with a Hirst-type pollen trap placed on the roof of the University Hospital. Specific IgE investigations were performed in children and adults with history of atopic diseases with deterioration between May and July. We analysed specific IgE for sp., birch, grasses, profilins, polcalcins and crossreacting carbohydrates.

RESULTS

We found abundant growth of and pollen was detected from early June to mid-July with a maximum pollen concentration of 31 pollen/m. Out of 138 patients (63 female, 69 children/adolescents), 95 (69%) had seasonal allergic rhinitis, 84 (61%) asthma, and 43 (31%) atopic dermatitis. Sensitization to was shown in 59 (42%). There were no significant differences between age groups. In 59% of patients sensitized (35/59), there was no sensitization to possibly cross-reacting structures.

CONCLUSION

Sensitization to pollen could be detected in 42% of our patients with atopic diseases, suggesting allergenic potential of this neophyte. In the context of further spread with climate change, eradication strategies and population-based sensitization studies are needed.