Prenzel Freerk, Treudler Regina, Lipek Tobias, Vom Hove Maike, Kage Paula, Kuhs Simone, Kaiser Thorsten, Bastl Maximilian, Bumberger Jan, Genuneit Jon, Hornick Thomas, Klotz Stefan, Zarnowski Julia, Boege Maren, Zebralla Veit, Simon Jan-Christoph, Dunker Susanne
Leipziger Interdisciplinary Center for Allergy (LICA), Comprehensive Allergy Center, Leipzig, Germany.
University of Leipzig, Medical Center, Department of Pediatrics, Leipzig, Germany.
J Asthma Allergy. 2022 Sep 1;15:1217-1226. doi: 10.2147/JAA.S373177. eCollection 2022.
is one of the world's most invasive species with a globally problematic spread. Pollen is dispersed locally and partially airborne. We aimed at investigating if (i) pollen can be detected in relevant quantity in the air and if (ii) sensitization to can be detected in patients with seasonal exacerbation of atopic diseases.
We recorded distribution of in Leipzig, Germany. In 2019 and 2020, pollen was collected with a Hirst-type pollen trap placed on the roof of the University Hospital. Specific IgE investigations were performed in children and adults with history of atopic diseases with deterioration between May and July. We analysed specific IgE for sp., birch, grasses, profilins, polcalcins and crossreacting carbohydrates.
We found abundant growth of and pollen was detected from early June to mid-July with a maximum pollen concentration of 31 pollen/m. Out of 138 patients (63 female, 69 children/adolescents), 95 (69%) had seasonal allergic rhinitis, 84 (61%) asthma, and 43 (31%) atopic dermatitis. Sensitization to was shown in 59 (42%). There were no significant differences between age groups. In 59% of patients sensitized (35/59), there was no sensitization to possibly cross-reacting structures.
Sensitization to pollen could be detected in 42% of our patients with atopic diseases, suggesting allergenic potential of this neophyte. In the context of further spread with climate change, eradication strategies and population-based sensitization studies are needed.
是世界上最具入侵性的物种之一，其传播在全球范围内造成问题。花粉在当地传播且部分通过空气传播。我们旨在调查：（i）空气中是否能检测到相关数量的花粉；（ii）在特应性疾病季节性加重的患者中是否能检测到对 的致敏情况。
我们记录了德国莱比锡 的分布情况。在2019年和2020年，使用放置在大学医院屋顶的赫斯特型花粉捕集器收集花粉。对5月至7月病情恶化的有特应性疾病史的儿童和成人进行特异性IgE检测。我们分析了针对 属、桦树、草、肌动蛋白结合蛋白、钙结合蛋白和交叉反应碳水化合物的特异性IgE。
我们发现 大量生长，6月初至7月中旬检测到花粉，最大花粉浓度为每立方米31粒花粉。138例患者（63名女性，69名儿童/青少年）中，95例（69%）患有季节性过敏性鼻炎，84例（61%）患有哮喘，43例（31%）患有特应性皮炎。59例（42%）显示对 致敏。各年龄组之间无显著差异。在致敏的患者中，59%（35/59）对可能交叉反应的结构无致敏。
在我们42%的特应性疾病患者中检测到对 花粉的致敏，表明这种新植物具有致敏潜力。在气候变化导致其进一步传播的背景下，需要根除策略和基于人群的致敏研究。
