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中国上海医生对老年患者不适当处方的认知、态度及感知障碍

Physicians' Knowledge, Altitudes, and Perceived Barriers of Inappropriate Prescribing for Older Patients in Shanghai, China.

作者信息

Yuan Jing, Yin Guizhi, Gu Meng, Lu Kevin Z, Jiang Bin, Li Minghui

机构信息

Minhang Hospital and Department of Clinical Pharmacy at School of Pharmacy, Fudan University, Shanghai, China.

Department of Cardiology, Minhang Hospital, Fudan University, Shanghai, China.

出版信息

Front Pharmacol. 2022 Aug 22;13:821847. doi: 10.3389/fphar.2022.821847. eCollection 2022.

Abstract

Inappropriate medication use is common around the world, particularly among older patients, and, despite potentially being preventable, often leads to adverse clinical and economic outcomes. However, there is a dearth of information regarding this prominent issue in China. To evaluate the extent to which the physician can correctly identify potentially inappropriate medication (PIM) in older patients and to understand physicians' attitudes towards improving PIM knowledge. An online, cross-sectional survey was conducted anonymously among practicing physicians in China from November through December 2020. Knowledge of PIM was accessed using seven clinical vignettes covering a wide variety of therapeutic areas. Source of information and perceived barriers regarding PIM were also evaluated. We performed the ordinary least square regression analysis to understand the potential factors related to physicians' knowledge of PIM. A total of 597 study participants were included in the analysis. More than half of them had never heard of any screening tool for PIMs ( = 328, 54.9%) and the most frequently acknowledged tool was the China PIM Criteria ( = 259, 43.4%). For the seven clinical vignettes testing physicians' knowledge on the medications that should be generally avoided in older patients, the mean score was 2.91 points out of 7 (SD: 1.32), with the median score of three points (IQR: 2-4). Only one-third of the respondents were feeling confident when prescribing for older patients ( = 255, 35.08%). Package inserts have been used as the major source of PIM information (always, = 177, 29.65%; frequently, = 286, 47.91%). Perceived barriers to appropriate prescribing include polypharmacy ( = 460, 77.05%), lack of formal education on prescribing for the older patients ( = 428, 71.69%). In this online survey evaluating physicians' ability to detect PIM for older patients, approximately 40% of PIM were recognized, suggesting an insufficient level of knowledge about appropriate prescribing.

摘要

不恰当用药在全球都很常见,尤其是在老年患者中,而且尽管有可能预防,但往往会导致不良的临床和经济后果。然而,在中国,关于这个突出问题的信息却很匮乏。为了评估医生正确识别老年患者潜在不恰当用药(PIM)的程度,并了解医生对提高PIM知识的态度。2020年11月至12月,在中国在职医生中进行了一项匿名的在线横断面调查。使用涵盖广泛治疗领域的七个临床病例 vignettes 来评估对PIM的了解情况。还评估了关于PIM的信息来源和感知到的障碍。我们进行了普通最小二乘回归分析,以了解与医生对PIM知识相关的潜在因素。分析共纳入了597名研究参与者。其中超过一半的人从未听说过任何PIM筛查工具(n = 328,54.9%),最常被认可的工具是中国PIM标准(n = 259,43.4%)。对于测试医生关于老年患者通常应避免使用的药物知识的七个临床病例 vignettes,平均得分是7分中的2.91分(标准差:1.32),中位数得分是3分(四分位间距:2 - 4)。只有三分之一的受访者在为老年患者开处方时感到自信(n = 255,35.08%)。药品说明书一直是PIM信息的主要来源(总是,n = 177,29.65%;经常,n = 286,47.91%)。感知到的合理用药障碍包括多重用药(n = 460,77.05%)、缺乏针对老年患者处方的正规教育(n = 428,71.69%)。在这项评估医生检测老年患者PIM能力的在线调查中,约40%的PIM被识别出来,这表明对合理处方的知识水平不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a88c/9441490/67c8c5b129e8/fphar-13-821847-g001.jpg

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