Center for Drug Reevaluation, NMPA/NMPA Key Laboratory for Research and Evaluation of Pharmacovigilance, Beijing, 100022, P. R. China.
Strategic Support Force Characteristic Medical Center, Beijing, 100101, P. R. China.
BMC Med Educ. 2024 May 24;24(1):570. doi: 10.1186/s12909-024-05561-5.
Knowledge of pharmacovigilance (PV) and adverse drug reactions (ADRs) are the core competencies that healthcare students should acquire during their studies. The objective of this study was to assess attitudes towards and knowledge of PV and ADRs among healthcare students in China.
An online, cross-sectional survey was conducted nationally among healthcare students in China from April through October 2023. Knowledge of PV and ADRs was assessed using a questionnaire based on current PV guidelines. We performed logistic regression analysis to determine the potential factors related to knowledge of and attitudes towards PV and ADRs.
A total of 345 students were included in the analysis. Among the healthcare students who participated in the survey, 225 (65.22%) students correctly defined PV, while only 68 (19.71%) had a correct understanding of ADRs. Among all respondents included in the analysis, only 71 (20.58%) reported having taken a PV course. Pharmacy students were more likely to have taken PV courses at a university and to demonstrate superior knowledge compared to other healthcare students. The logistic regression model revealed that the significant predictors of a higher level of PV knowledge were being female (odds ratio [OR]: 1.76; 95% confidence interval (CI): 1.06-2.92; P value: 0.028) and having previously taken PV-related courses (OR: 2.00; 95% CI: 1.06-3.80; P value: 0.034).
This study revealed that healthcare students' knowledge of PV and ADRs is unsatisfactory. However, there were a limited number of universities providing PV education. Given the vital role of healthcare professionals in identifying and reporting ADRs, our findings raise significant concerns. Hence, more efforts should be made to enhance PV education for future healthcare professionals.
药物警戒（PV）和药物不良反应（ADR）知识是医学生在学习期间应掌握的核心能力。本研究的目的是评估中国医学生对 PV 和 ADR 的态度和知识。
2023 年 4 月至 10 月，我们在中国全国范围内对医学生进行了一项在线横断面调查。我们使用基于当前 PV 指南的问卷评估 PV 和 ADR 知识。我们进行了逻辑回归分析，以确定与 PV 和 ADR 知识和态度相关的潜在因素。
共有 345 名学生纳入分析。在参加调查的医学生中，225 名（65.22%）学生正确定义了 PV，而只有 68 名（19.71%）学生正确理解了 ADR。在所有纳入分析的受访者中，只有 71 名（20.58%）报告曾修过 PV 课程。与其他医学生相比，药学学生更有可能在大学修过 PV 课程，并且具有更丰富的知识。逻辑回归模型显示，PV 知识水平较高的显著预测因素是女性（比值比 [OR]：1.76；95%置信区间 [CI]：1.06-2.92；P 值：0.028）和之前修过 PV 相关课程（OR：2.00；95% CI：1.06-3.80；P 值：0.034）。
本研究表明，医学生对 PV 和 ADR 的知识掌握不足。然而，提供 PV 教育的大学数量有限。鉴于医疗保健专业人员在识别和报告 ADR 方面的重要作用，我们的研究结果令人担忧。因此，应加大力度为未来的医疗保健专业人员提供 PV 教育。
