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微导管保护下旋转削切术联合双导丝技术治疗严重左主干分叉病变钙化的安全性评估。

Safety Assessment of Microcatheter-Protected Rotational Atherectomy with the Double Guiding Catheter Technique for Severely Calcified Left Main Bifurcation.

机构信息

Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

出版信息

J Interv Cardiol. 2022 Aug 9;2022:1399510. doi: 10.1155/2022/1399510. eCollection 2022.

DOI:10.1155/2022/1399510
PMID:36072361
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9381278/
Abstract

BACKGROUND

Rotational atherectomy (RA) is a tool for calcium modification, but there is a risk of losing the side branch in left main coronary artery (LM) bifurcation lesions, resulting in disastrous consequences. Microcatheter-protected RA with the double guiding catheter (GC) technique for severely calcified LM bifurcations has been described previously, but its safety warrants further investigation.

METHODS

Various sizes of coronary calcification vascular simulators were utilized to model calcified LM bifurcation lesions for RA in in vitro. The damage to the side branch protective microcatheters and guidewires was accessed after microcatheter-protected RA with the double GC technique. In clinical practice, microcatheter-protected RA with the double GC technique was carried out in two patients.

RESULTS

In vitro, none of the protective microcatheters or guidewires were completely fractured, although the majority of them were damaged to varying degrees. In clinical practice, we successfully carried out two cases of percutaneous coronary intervention for severely calcified LM bifurcation with microcatheter-protected RA using the double GC technique.

CONCLUSION

RA of severely calcified LM bifurcation lesions may be successfully performed using microcatheter-protected RA with the double GC technique, potentially reducing the risk of side branch occlusion. Since majority of protective microcatheters or guidewires were damaged, there was still some risk, and it is recommended to use this technique only in highly selected patient population of severely calcified true (Medina 1, 1, 1) LM bifurcations.

摘要

背景

旋磨术(RA)是一种用于钙化修饰的工具,但在左主干冠状动脉(LM)分叉病变中存在丢失侧支的风险,导致灾难性后果。以前已经描述了使用双导引导管(GC)技术进行严重钙化的 LM 分叉病变的微导管保护 RA,但需要进一步研究其安全性。

方法

使用各种尺寸的冠状动脉钙化血管模拟器模拟 RA 治疗中的钙化 LM 分叉病变。评估双 GC 技术下微导管保护 RA 后对侧支保护微导管和导丝的损伤。在临床实践中,对两名患者进行了双 GC 技术下的微导管保护 RA。

结果

在体外,尽管大多数微导管和导丝都有不同程度的损坏,但没有一个微导管或导丝完全断裂。在临床实践中,我们成功地使用双 GC 技术对严重钙化的 LM 分叉病变进行了经皮冠状动脉介入治疗,采用了微导管保护 RA。

结论

使用双 GC 技术的微导管保护 RA 可能成功地对严重钙化的 LM 分叉病变进行 RA,从而降低侧支闭塞的风险。由于大多数保护微导管或导丝都受到了损坏,因此仍存在一定的风险,建议仅在严重钙化的真性(Medina 1,1,1)LM 分叉病变的高度选择患者人群中使用这种技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/00e156d9aa19/JITC2022-1399510.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/95e3efd73464/JITC2022-1399510.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/f4cdd6c490e1/JITC2022-1399510.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/8313f966b129/JITC2022-1399510.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/256023c21d1a/JITC2022-1399510.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/9d52ede8d4a1/JITC2022-1399510.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/00e156d9aa19/JITC2022-1399510.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/95e3efd73464/JITC2022-1399510.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/f4cdd6c490e1/JITC2022-1399510.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/8313f966b129/JITC2022-1399510.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/256023c21d1a/JITC2022-1399510.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/9d52ede8d4a1/JITC2022-1399510.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f38/9381278/00e156d9aa19/JITC2022-1399510.006.jpg

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