Comerford J A, Broe P J, Wilson I A, Bouchier-Hayes D J
Br J Surg. 1987 Jun;74(6):493-5. doi: 10.1002/bjs.1800740624.
Digital ischaemia in the presence of an otherwise well-perfused foot in the non-diabetic patient presents diagnostic problems especially as the manifestations are frequently evanescent. Eighty such patients (sixty men and twenty women aged 55-84 years) who presented to St. Laurence's Hospital from 1982 to 1985 inclusive were evaluated. Micro-embolization was inferred from the demonstration of a cardiac (20) or an arterial source (42) in 62 of 80 patients. In 14 of the remaining 18 patients a malignancy was diagnosed, which was found to be visceral cancer in 11 cases. Indium platelet scanning revealed platelet aggregation in 14 of 26 patients examined. Laboratory evidence of abnormalities of platelet aggregation or blood coagulation was found in only 6 patients. There have been no further symptoms in 37 patients who have been treated surgically or in 17 of 21 patients who have been treated with either anticoagulation or antiplatelet therapy.
在非糖尿病患者中，足部其他部位血供良好却出现手指缺血的情况会带来诊断难题，尤其是因为其表现常常转瞬即逝。对1982年至1985年（含）期间就诊于圣劳伦斯医院的80例此类患者（60名男性和20名女性，年龄55 - 84岁）进行了评估。80例患者中有62例通过显示心脏（20例）或动脉源性（42例）微栓塞得以推断。其余18例患者中有14例被诊断患有恶性肿瘤，其中11例为内脏癌。铟血小板扫描显示，在接受检查的26例患者中有14例存在血小板聚集。仅6例患者有血小板聚集或血液凝固异常的实验室证据。接受手术治疗的37例患者或接受抗凝或抗血小板治疗的21例患者中的17例均未再出现症状。
