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预测外周动脉疾病患者的步行能力。

Predictors of walking capacity in patients with peripheral arterial disease.

机构信息

Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Eskişehir Osmangazi University, Eskişehir, Turkey.

Faculty of Physical Therapy and Rehabilitation, Dokuz Eylul University, Izmir, Turkey.

出版信息

Wien Klin Wochenschr. 2024 Feb;136(3-4):94-100. doi: 10.1007/s00508-022-02078-z. Epub 2022 Sep 8.

DOI:10.1007/s00508-022-02078-z
PMID:36074178
Abstract

BACKGROUND

Walking capacity is severely impaired in patients with peripheral arterial disease (PAD). Given the prognostic importance of walking capacity, the level of evidence on possible predictors of walking capacity in patients with PAD is insufficient.

AIMS

To investigate the predictors of walking capacity in patients with PAD.

METHODS

A total of 51 patients with PAD were included in this cross-sectional study. Walking capacity was determined with 6‑minute walk test (6MWT) and walking impairment questionnaire (WIQ). Functional mobility was assessed with repeated sit-to-stand test (RSS) and timed up and go test (TUG). Hand-held dynamometer was used to measurement lower extremity muscle strength. Balance was assessed with Biodex Balance System-limit of stability (BBS-LOS). Fatigue was evaluated with fatigue impact scale (FIS).

RESULTS

There was a strong correlation between 6MWT walking distance and WIQ, two methods of assessing walking capacity (r = 0.835 p < 0.001). The 6MWT was correlated with RSS, TUG, lower extremity muscle strength, BBS-LOS and FIS. The WIQ was correlated with RSS, TUG, BBS-LOS and FIS. The RSS and FIS were independent determinants of the 6MWT and WIQ, accounting for 68% and 57% of the variance, respectively.

CONCLUSION

This study demonstrated that functional mobility and fatigue were independent predictors of walking capacity in patients with PAD. Both subjective and objective measurement methods can be used for determining the level of walking capacity in the patients with PAD.

摘要

背景

外周动脉疾病(PAD)患者的步行能力严重受损。鉴于步行能力的预后重要性,PAD 患者步行能力的可能预测因素的证据水平不足。

目的

调查 PAD 患者步行能力的预测因素。

方法

本横断面研究共纳入 51 例 PAD 患者。采用 6 分钟步行试验(6MWT)和步行障碍问卷(WIQ)测定步行能力。采用重复坐站试验(RSS)和计时起立行走试验(TUG)评估功能性移动能力。使用手持测力计测量下肢肌肉力量。使用 Biodex 平衡系统-稳定性极限(BBS-LOS)评估平衡。使用疲劳影响量表(FIS)评估疲劳。

结果

6MWT 步行距离与 WIQ(评估步行能力的两种方法)之间存在很强的相关性(r=0.835,p<0.001)。6MWT 与 RSS、TUG、下肢肌肉力量、BBS-LOS 和 FIS 相关。WIQ 与 RSS、TUG、BBS-LOS 和 FIS 相关。RSS 和 FIS 是 6MWT 和 WIQ 的独立决定因素,分别占方差的 68%和 57%。

结论

本研究表明,功能性移动能力和疲劳是 PAD 患者步行能力的独立预测因素。主观和客观测量方法均可用于确定 PAD 患者的步行能力水平。

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Comparing 6-minute walk versus treadmill walking distance as outcomes in randomized trials of peripheral artery disease.比较 6 分钟步行和跑步机步行距离作为周围动脉疾病随机试验的结果。
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Relationship between gait speed and physical function in patients with symptomatic peripheral artery disease.
症状性外周动脉疾病患者的步速与身体功能之间的关系。
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Association of 6-Minute Walk Performance and Physical Activity With Incident Ischemic Heart Disease Events and Stroke in Peripheral Artery Disease.外周动脉疾病患者6分钟步行表现及身体活动与缺血性心脏病事件和中风发生的关联
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