Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, 252-0374, Japan.
J Interv Card Electrophysiol. 2023 Mar;66(2):485-492. doi: 10.1007/s10840-022-01360-4. Epub 2022 Sep 8.
The lesion size index (LSI) predicts radiofrequency (RF) ablation lesion size and is an established parameter for pulmonary vein isolation. However, the effectiveness and safety of LSI for cavotricuspid isthmus (CTI) linear ablation remain unclear.
This single-center retrospective study included 50 of patients (67 ± 10 years, 68% male) who underwent de novo CTI linear ablation between July 2020 and December 2020. The LSI target was set at 5.0 and 4.0 for the anterior and posterior segments, respectively. Acute procedural parameters of ablation were evaluated.
Acute bidirectional CTI block was achieved in all patients with an RF application time of 4.0 min (3.1-5.0 min), RF application number of 15 ± 7, and length of CTI of 36.9 ± 9.3 mm. First-pass bidirectional conduction block of the CTI was achieved in 39/50 (78%) patients. No major complications were observed. The contact force (CF) per application was significantly lower in the gap tag group than in the non-gap tag group (7 g [7-8 g] vs. 10 g [7-12 g], P = 0.0284).
LSI-guided CTI linear ablation is an effective and safe treatment approach. CF affects gap formation, even when the target LSI is the same.
病灶大小指数(LSI)可预测射频(RF)消融病灶大小,是肺静脉隔离的既定参数。然而,LSI 对三尖瓣环峡部(CTI)线性消融的有效性和安全性仍不清楚。
这项单中心回顾性研究纳入了 50 例(67±10 岁,68%为男性)于 2020 年 7 月至 2020 年 12 月期间行首次 CTI 线性消融的患者。LSI 目标在前部和后部分别设定为 5.0 和 4.0。评估消融的急性程序参数。
所有患者均实现了急性双向 CTI 阻断,RF 应用时间为 4.0 分钟(3.1-5.0 分钟),RF 应用次数为 15±7,CTI 长度为 36.9±9.3 毫米。39/50(78%)患者首次实现 CTI 双向传导阻断。未观察到主要并发症。在有间隙标记的组中,每个应用的接触力(CF)显著低于无间隙标记的组(7g[7-8g]比 10g[7-12g],P=0.0284)。
LSI 指导的 CTI 线性消融是一种有效且安全的治疗方法。即使目标 LSI 相同,CF 也会影响间隙的形成。