- Universidade Federal Fluminense, Saúde Materno-Infantil - Rio de Janeiro - RJ - Brasil.
- Instituto Nacional do Câncer, Cirurgia Pediátrica Oncológica - Rio de Janeiro - RJ - Brasil.
Rev Col Bras Cir. 2022 Sep 2;49:e20223341. doi: 10.1590/0100-6991e-20223341-en. eCollection 2022.
sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy. The complete surgical resection of the tumor associated with coccygectomy is the standard treatment and chemotherapy in different stages are necessary. Follow-up consists of serial exam: tumor markers, imaging searching to possible metastasis sites, in addition to a complete physical examination.
a descriptive, retrospective, study was carried out by analyzing a chart of 25 patients of two different reference children cancer center; with TSC in the State of Rio de Janeiro from 2004 to 2019. The clinical and epidemiological data collected were described and a comparison was made between these two centers studied.
the sociodemographic characteristics found were similar to those described in the medical literature. Data related to treatment and follow-up, such as the use of chemotherapy, use of specific imaging tests, digital rectal examination, and outpatient follow-up, differed between the two centers studied. There was a 25% loss of follow-up.
the characteristic of being a non-cancer center can interfere with the full application of the current protocol for the treatment of sacrococcygeal teratoma. The knowledge of the data of the studied cases can allow the optimization of the approach of the patients with this pathology and generate discussions about the integral application of the specific therapeutic protocol in the medical centers that are qualified for such treatment.
骶尾部畸胎瘤(TSC)是新生儿期最常见的肿瘤。甲胎蛋白是一种重要的肿瘤标志物,在随访期间用作恶性肿瘤的标志物。肿瘤的完全手术切除联合尾骨切除术是标准治疗方法,不同阶段需要化疗。随访包括连续检查:肿瘤标志物、寻找可能转移部位的影像学检查,以及完整的体格检查。
通过分析 2004 年至 2019 年在里约热内卢州的两家不同参考儿童医院的 25 名 TSC 患者的图表,进行了一项描述性、回顾性研究。对收集的临床和流行病学数据进行了描述,并对这两个研究中心进行了比较。
发现的社会人口统计学特征与文献中描述的相似。治疗和随访方面的数据,如化疗的使用、特定影像学检查、直肠指检和门诊随访,在两个研究中心之间存在差异。有 25%的患者随访丢失。
作为一个非癌症中心的特点可能会干扰骶尾部畸胎瘤治疗当前方案的全面应用。研究病例的数据知识可以优化这类患者的治疗方法,并就特定治疗方案在有资格进行此类治疗的医疗中心的全面应用展开讨论。