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大鼠中脑边缘系统中对酪胺和间酪胺的浓度:其区域分布及单胺氧化酶抑制作用的影响。

The concentration of p- and m-tyramine in the rat mesolimbic system: its regional distribution and effect of monoamine oxidase inhibition.

作者信息

Sardar A, Juorio A V, Boulton A A

出版信息

Brain Res. 1987 Jun 2;412(2):370-4. doi: 10.1016/0006-8993(87)91145-0.

DOI:10.1016/0006-8993(87)91145-0
PMID:3607473
Abstract

The concentrations of p-tyramine and m-tyramine have been determined in 6 brain areas from the mesolimbic system by a specific and sensitive mass spectrometric technique. p- and m-Tyramine are unevenly distributed amongst these nuclei. The highest concentrations of p-tyramine were measured in the olfactory tubercle followed by the nucleus accumbens and septal nuclei while for m-tyramine the concentrations decreased in the following order: olfactory tubercle, nucleus accumbens, amygdala, septal nuclei and nucleus tractus diagonalis.

摘要

已通过一种特异且灵敏的质谱技术测定了中脑边缘系统6个脑区中对酪胺和间酪胺的浓度。对酪胺和间酪胺在这些核团中的分布并不均匀。对酪胺浓度最高的是嗅结节,其次是伏隔核和隔核;而间酪胺的浓度按以下顺序降低:嗅结节、伏隔核、杏仁核、隔核和斜角带核。

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