采用高效液相色谱法、液相色谱-串联质谱法测定土耳其蜂蜜产品中的真菌毒素，并对真菌毒素进行健康风险评估。
Determination of mycotoxins by HPLC, LC-MS/MS and health risk assessment of the mycotoxins in bee products of Turkey.
机构信息
Department of Nutrition and Dietetics, Institute of Health Sciences, Istanbul Medipol University, Kavacik, 34810 Istanbul, Turkey.
Department of Biochemistry, School of Pharmacy, Istanbul Medipol University, Kavacik, 34810 Istanbul, Turkey.
出版信息
Food Chem. 2023 Jan 30;400:134086. doi: 10.1016/j.foodchem.2022.134086. Epub 2022 Sep 5.
The aim of this study is to determine the levels of deoxynivalenol (DON), HT-2 toxin (HT2), T-2 toxin (T2), and ochratoxin A (OTA) in bee products (bee pollen, propolis, honey and royal jelly) available in Turkey. In addition, exposure and health risk assessments were performed to identify the potential health risk of these mycotoxins. The mycotoxins were analyzed by high-performance liquid chromatography (HPLC) with a UV detector and positive samples were confirmed with liquid chromatography-tandem mass spectrometry (LC-MS/MS). The most common mycotoxins in all bee products were DON and T-2 toxin, with mean concentrations of 1.601 and 0.704 µg/per kg dry sample, respectively, followed by OTA and HT-2 toxin. It was determined that the mycotoxins taken as a result of consuming bee products in specified amounts do not pose a risk to health.
本研究旨在测定土耳其市售的蜂产品（蜂花粉、蜂胶、蜂蜜和蜂王浆）中脱氧雪腐镰刀菌烯醇（DON）、HT-2 毒素（HT2）、T-2 毒素（T2）和赭曲霉毒素 A（OTA）的含量。此外，还进行了暴露和健康风险评估，以确定这些霉菌毒素的潜在健康风险。采用高效液相色谱法（HPLC）结合紫外检测器对霉菌毒素进行分析，阳性样品用液相色谱-串联质谱法（LC-MS/MS）进行确证。所有蜂产品中最常见的霉菌毒素是 DON 和 T-2 毒素，其在干样中的平均浓度分别为 1.601 和 0.704 µg/kg，其次是 OTA 和 HT-2 毒素。结果表明，按规定量摄入蜂产品所摄入的霉菌毒素不会对健康造成危害。
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