Jagu A
Service de Cardiologie, Groupe Hospitalier Paris Saint Joseph, 185, rue Raymond Losserand, 75014 Paris, France.
Ann Cardiol Angeiol (Paris). 2022 Nov;71(5):304-308. doi: 10.1016/j.ancard.2022.07.007. Epub 2022 Sep 6.
Over the last decade, cancer mortality has decreased considerably, particularly in breast cancer thanks to better screening techniques and better therapeutic management. The significant increase in patient survival has led to the appearance of a certain number of events due to the side effects of the therapies used. Cardiovascular disease is the most frequently observed side effect in breast cancer, due to the direct toxicity of anti-cancer therapies but also due to traditional cardiovascular risk factors common to both of diseases. Anthracyclines, anti-HER2 therapies, chest radiotherapy and hormone therapy are the main causes of cardiotoxicity in breast cancer. It is important to know the rate of follow-up for cardiotoxicity screening and management.
在过去十年中，癌症死亡率大幅下降，尤其是乳腺癌，这得益于更好的筛查技术和治疗管理。患者生存率的显著提高导致了因所用治疗方法的副作用而出现的一些情况。心血管疾病是乳腺癌中最常见的副作用，这是由于抗癌治疗的直接毒性，也由于这两种疾病共有的传统心血管危险因素。蒽环类药物、抗HER2治疗、胸部放疗和激素治疗是乳腺癌心脏毒性的主要原因。了解心脏毒性筛查和管理的随访率很重要。
