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大麻素呕吐综合征和大麻戒断综合征:急诊科大麻相关综合征管理综述

Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department.

作者信息

Razban Mohammad, Exadaktylos Aristomenis K, Santa Vincent Della, Heymann Eric P

机构信息

Department of Internal Medicine, University Hospital of Geneva, Geneva, Switzerland.

University of Bern, Bern, Switzerland.

出版信息

Int J Emerg Med. 2022 Sep 8;15(1):45. doi: 10.1186/s12245-022-00446-0.

DOI:10.1186/s12245-022-00446-0
PMID:36076180
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9454163/
Abstract

BACKGROUND

Cannabis-related medical consultations are increasing worldwide, a non-negligible public health issue; patients presenting to acute care traditionally complain of abdominal pain and vomiting. Often recurrent, these frequent consultations add to the congestion of already chronically saturated emergency department(s) (ED). In order to curb this phenomenon, a specific approach for these patients is key, to enable appropriate treatment and long-term follow-up.

OBJECTIVES

This study reviews cannabinoid hyperemesis syndrome (CHS) and cannabis withdrawal syndrome (CWS), in a bid to help promote better understanding and handling of pathologies associated with chronic cannabis use. Following a literature review, we present a novel therapeutic algorithm aimed at guiding clinicians, in a bid to improve long-term outcomes and prevent recurrences.

METHODS

Using the keywords "Cannabis," "Hyperemesis," "Syndrome," "Withdrawal," and "Emergency Medicine," we completed a literature review of three different electronic databases (PubMed®, Google scholar®, and Cochrane®), up to November 2021.

RESULTS

Although often presenting with similar symptoms such as abdominal pain and vomiting, cannabinoid hyperemesis syndrome (CHS) and cannabis withdrawal syndrome (CWS) are the result of two differing pathophysiological processes. Distinguishing between these two syndromes is essential to provide appropriate symptomatic options.

CONCLUSION

The correct identification of the underlying cannabis-related syndrome, and subsequent therapeutic choice, may help decrease ED presentations. Our study emphasizes the importance of both acute care and long-term outpatient follow-up, as key processes in cannabis-related disorder treatment.

摘要

背景

全球范围内,与大麻相关的医疗咨询正在增加,这是一个不可忽视的公共卫生问题;传统上,前往急诊就诊的患者常主诉腹痛和呕吐。这些频繁的咨询往往反复发作,加剧了本已长期饱和的急诊科的拥堵。为了遏制这一现象,针对这些患者采取特定方法至关重要,以便进行适当治疗和长期随访。

目的

本研究回顾大麻素呕吐综合征(CHS)和大麻戒断综合征(CWS),以促进对与长期使用大麻相关病症的更好理解和处理。在文献综述之后,我们提出一种新颖疗法算法,旨在指导临床医生,以改善长期治疗效果并预防复发。

方法

使用关键词“大麻”“呕吐”“综合征”“戒断”和“急诊医学”,我们对三个不同电子数据库(PubMed®、谷歌学术®和考克兰®)截至2021年11月的文献进行了综述。

结果

尽管大麻素呕吐综合征(CHS)和大麻戒断综合征(CWS)常表现出腹痛和呕吐等相似症状,但它们是两种不同病理生理过程的结果。区分这两种综合征对于提供适当的对症治疗选择至关重要。

结论

正确识别潜在的与大麻相关的综合征并做出后续治疗选择,可能有助于减少急诊就诊。我们的研究强调了急性护理和长期门诊随访作为大麻相关疾病治疗关键过程的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b1/9454163/0a6f4faeb27e/12245_2022_446_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b1/9454163/c580650485e4/12245_2022_446_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b1/9454163/0a6f4faeb27e/12245_2022_446_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b1/9454163/c580650485e4/12245_2022_446_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b1/9454163/0a6f4faeb27e/12245_2022_446_Fig2_HTML.jpg

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Acute cannabis intoxication in the emergency department: the effect of legalization.急诊科急性大麻中毒:合法化的影响。
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Topical capsaicin for the treatment of cannabinoid hyperemesis syndrome, a systematic review and meta-analysis.辣椒素局部治疗大麻素呕吐综合征的系统评价和荟萃分析。
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