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竹笋(中竹)副产品中的多糖通过与肠道微生物群相互作用减轻小鼠抗生素相关性腹泻。

Polysaccharides from Bamboo Shoot ( Nakal) Byproducts Alleviate Antibiotic-Associated Diarrhea in Mice through Their Interactions with Gut Microbiota.

作者信息

Chen Canhui, Guan Xuefang, Liu Xiaoyan, Zhuang Weijing, Xiao Yiqian, Zheng Yafeng, Wang Qi

机构信息

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

Institute of Agricultural Engineering, Fujian Academy of Agricultural Sciences, Fuzhou 350003, China.

出版信息

Foods. 2022 Aug 31;11(17):2647. doi: 10.3390/foods11172647.

DOI:10.3390/foods11172647
PMID:36076830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9455761/
Abstract

A water-soluble polysaccharide BSP was extracted from the basal part of bamboo shoot, a main by-product of bamboo shoot processing. BSP is composed of glucose (72.8%), xylose (19.43%) and a small amount of galactose, arabinose, glucuronic acid and mannose. The effects of BSP on mice with antibiotic-associated diarrhea (AAD) were investigated. The mice fed with BSP exhibited significant higher bodyweight gain, lower pH value and higher concentrations of SCFAs in the feces compared with those fed with saline. BSP administration reduced the inflammatory cells in the small intestine and colon in the AAD mice, and / ratio in the gut was decreased from 0.56 to 0.19. Moreover, BSP administration affected the composition and diversity of the gut microbiota in the AAD mice, particularly on the improvement of beneficial bacteria such as , and . Our results suggest that the polysaccharides from bamboo shoot by-products could be an attractive natural component for gut health and AAD treatment.

摘要

从竹笋加工的主要副产品竹笋基部提取了一种水溶性多糖BSP。BSP由葡萄糖(72.8%)、木糖(19.43%)以及少量半乳糖、阿拉伯糖、葡萄糖醛酸和甘露糖组成。研究了BSP对患有抗生素相关性腹泻(AAD)小鼠的影响。与喂食生理盐水的小鼠相比,喂食BSP的小鼠体重增加显著更高,粪便pH值更低,短链脂肪酸浓度更高。给予BSP可减少AAD小鼠小肠和结肠中的炎症细胞,肠道中/比值从0.56降至0.19。此外,给予BSP影响了AAD小鼠肠道微生物群的组成和多样性,特别是对有益菌如、和的改善。我们的结果表明,竹笋副产品中的多糖可能是一种对肠道健康和AAD治疗有吸引力的天然成分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/e61d54f78be5/foods-11-02647-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/0acb1b8c0ea9/foods-11-02647-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/b5adfb6d069d/foods-11-02647-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/80ee6cbbdb84/foods-11-02647-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/e01311c0ad87/foods-11-02647-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/e61d54f78be5/foods-11-02647-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/0acb1b8c0ea9/foods-11-02647-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/b5adfb6d069d/foods-11-02647-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/80ee6cbbdb84/foods-11-02647-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/e01311c0ad87/foods-11-02647-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb9b/9455761/e61d54f78be5/foods-11-02647-g005.jpg

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