Department of Physical Chemistry and Technology of Polymers, Faculty of Chemistry, Silesian University of Technology, Strzody 9, 44-100 Gliwice, Poland.
Int J Mol Sci. 2022 Sep 1;23(17):9932. doi: 10.3390/ijms23179932.
This review presents an overview of methods for preparing chitosan-derived porous materials and discusses their potential applications. This family of materials has garnered significant attention owing to their biocompatibility, nontoxicity, antibacterial properties, and biodegradability, which make them advantageous in a wide range of applications. Although individual porous chitosan-based materials have been widely discussed in the literature, a summary of all available methods for preparing materials based on pure chitosan, along with their structural characterization and potential applications, has not yet been presented. This review discusses five strategies for fabricating porous chitosan materials, i.e., cryogelation, freeze-drying, sol-gel, phase inversion, and extraction of a porogen agent. Each approach is described in detail with examples related to the preparation of chitosan materials. The influence of the fabrication method on the structure of the obtained material is also highlighted herein. Finally, we discuss the potential applications of the considered materials.
这篇综述介绍了制备壳聚糖衍生多孔材料的方法，并讨论了它们的潜在应用。由于壳聚糖具有生物相容性、无毒、抗菌和可生物降解等特性，因此在广泛的应用中具有优势，这使得该材料家族受到了极大关注。尽管文献中已经广泛讨论了个别多孔壳聚糖基材料，但尚未对所有可用的纯壳聚糖基材料的制备方法进行总结，包括它们的结构表征和潜在应用。本文综述了制备多孔壳聚糖材料的五种策略，即冷冻凝胶化、冷冻干燥、溶胶-凝胶、相转化和致孔剂提取。每种方法都详细描述，并举例说明了壳聚糖材料的制备。本文还重点介绍了制备方法对所得材料结构的影响。最后，我们讨论了所考虑材料的潜在应用。
