The Pleiotropy of Gene Products and Function.

PAX5, a member of the Paired Box (PAX) transcription factor family, is an essential factor for B-lineage identity during lymphoid differentiation. Mechanistically, PAX5 controls gene expression profiles, which are pivotal to cellular processes such as viability, proliferation, and differentiation. Given its crucial function in B-cell development, aberrant expression also correlates with hallmark cancer processes leading to hematological and other types of cancer lesions. Despite the well-established association of in the development, maintenance, and progression of cancer disease, the use of as a cancer biomarker or therapeutic target has yet to be implemented. This may be partly due to the assortment of expressed products, which layers the complexity of their function and role in various regulatory networks and biological processes. In this review, we provide an overview of the reported data describing products, their regulation, and function in cellular processes, cellular biology, and neoplasm.