The Department of Information Systems, and the Department of Health Systems Management, The Max Stern Emek Yezreel College, Jezreel Valley 1930600, Israel.
Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Int J Environ Res Public Health. 2022 Aug 24;19(17):10521. doi: 10.3390/ijerph191710521.
The cancer burden in Israel is substantial. Recently calculated population attributable fractions (PAFs) for modifiable cancer risk factors in the US and the UK have indicated much room for prevention. Our aim was to estimate PAFs for selected modifiable cancer risk factors in Israel. Exposure data on selected modifiable risk factors were based on national health surveys conducted in 2013-2015. Data on invasive cancer incidence in 2015 were retrieved from the Israel National Cancer Registry (INCR). Relative risks (RRs) for specific cancer sites were retrieved from the scientific literature. PAFs were calculated for selected modifiable risk factors using an approximate formula. In 2015, 21% of all invasive cancer cases in Israel were attributed to smoking, 9% to excess body weight, and 1.5% to alcohol intake. Moreover, 32% of all invasive cancer cases were attributed to all modifiable risk factors (combined) included in our study. Quantifying the contribution of modifiable risk factors to the incidence of certain cancer types in Israel offers an opportunity for primary prevention and enables informed decision-making with respect to the prioritization of interventions.
以色列的癌症负担很大。最近，美国和英国计算的可改变癌症风险因素的人群归因分数（PAFs）表明，有很大的预防空间。我们的目的是估计以色列选定的可改变癌症风险因素的 PAFs。 选定的可改变风险因素的暴露数据基于 2013-2015 年进行的国家健康调查。2015 年侵袭性癌症发病率的数据从以色列国家癌症登记处（INCR）检索。特定癌症部位的相对风险（RRs）从科学文献中检索。使用近似公式计算选定的可改变风险因素的 PAFs。 2015 年，以色列所有侵袭性癌症病例中有 21%归因于吸烟，9%归因于超重，1.5%归因于饮酒。此外，我们研究中包括的所有可改变的风险因素（综合）导致 32%的所有侵袭性癌症病例。 定量评估可改变的风险因素对某些癌症类型在以色列发病率的影响为一级预防提供了机会，并使我们能够做出明智的决策，确定干预措施的优先顺序。
