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印度尼西亚中爪哇省三宝垄市孕妇头发中汞水平的首次暴露评估及其对出生体重和长度的影响。

The First Exposure Assessment of Mercury Levels in Hair among Pregnant Women and Its Effects on Birth Weight and Length in Semarang, Central Java, Indonesia.

机构信息

Department of Physiology, Faculty of Medicine, Diponegoro University, Semarang 50275, Indonesia.

Department of Public Health, Faculty of Medicine, Diponegoro University, Semarang 50275, Indonesia.

出版信息

Int J Environ Res Public Health. 2022 Aug 27;19(17):10684. doi: 10.3390/ijerph191710684.

DOI:10.3390/ijerph191710684
PMID:36078404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9518431/
Abstract

(1) Background: Methylmercury (MeHg) exposure during pregnancy is an important issue due to its possible adverse health effects on fetus. To contribute the development of assessment system of Hg exposure through fish consumption and health effects on children, we examined the hair Hg levels in pregnant women and birth weight and length. (2) Methods: In 2018, a cohort study was conducted on 118 pregnant women-infant pairs from six community health centers in the northern coastal area in Central Java Indonesia. Data on mothers' characteristics during pregnancy, birth outcomes, and fish consumption were collected. Total Hg concentrations were determined from hair samples. (3) Results: The median (min-max) of the maternal hair Hg level was 0.434 (0.146-8.105) µg/g. Pregnant women living in lowland areas, near the sea, showed higher hair Hg concentration and fish consumption than those in highland areas {[0.465 (0.146-8.105) vs. 0.385 (0.150-1.956) µg/g; = 0.043] and [(85.71 (0-500.0) vs. 49.76 (0.0-428.57) g/day; < 0.01], respectively}. The maternal hair Hg level had no association with baby's birth weight and length. (4) Conclusions: The median maternal hair Hg is at a low level and had no association with infant birth weight and length in this study subjects.

摘要

(1) 背景:由于孕期甲基汞(MeHg)暴露可能对胎儿健康产生不良影响,因此这是一个重要问题。为了促进通过鱼类消费评估汞暴露和对儿童健康影响的评估体系的发展,我们检测了孕妇头发中的汞水平以及婴儿的出生体重和身长。(2) 方法:2018 年,在印度尼西亚中爪哇北部沿海地区的六个社区卫生中心对 118 对孕妇-婴儿进行了队列研究。收集了母亲在孕期的特征、出生结局和鱼类消费的数据。从头发样本中测定总汞浓度。(3) 结果:母亲头发汞水平的中位数(最小值-最大值)为 0.434(0.146-8.105)µg/g。居住在低海拔地区、靠近海边的孕妇头发汞浓度和鱼类消费高于高海拔地区的孕妇 [(0.465(0.146-8.105)比 0.385(0.150-1.956)µg/g; = 0.043] 和 [(85.71(0-500.0)比 49.76(0.0-428.57)g/天; < 0.01]。母亲头发汞水平与婴儿的出生体重和身长无关。(4) 结论:在本研究中,母亲头发汞的中位数处于较低水平,与婴儿的出生体重和身长无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e3/9518431/1d22df63c6dc/ijerph-19-10684-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e3/9518431/84d8cb87434b/ijerph-19-10684-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e3/9518431/1d22df63c6dc/ijerph-19-10684-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e3/9518431/84d8cb87434b/ijerph-19-10684-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e3/9518431/1d22df63c6dc/ijerph-19-10684-g003.jpg

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Prenatal Mercury Exposure in Pregnant Women from Suriname's Interior and Its Effects on Birth Outcomes.苏里南内陆孕妇产前汞暴露及其对出生结局的影响。
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