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[关节内及关节周围过氧化氢酶在临床骨科实践中的应用]

[Use of intra- and peri-articular peroxide dismutase in clinical orthopedic practice].

作者信息

Pessina R, Renoldi M, Bertolini B, Der Asvazadurian A

出版信息

Chir Ital. 1987 Feb;39(1):107-14.

PMID:3607975
Abstract

The authors report the results of intra- and peri-articular orgotein treatment in 30 arthritic patients. The patients were examined before, during and at the end of the course of treatment and showed substantial improvement. Negative and mediocre results were more frequent in cases of gonarthrosis. This finding may be accounted for by the severity of the articular situation in these patients, though orgotein treatment is also preferred in such cases, as it avoids iatrogenic damage. The authors also make it clear that no benefit can be achieved by combining the use of local anaesthetics with the orgotein treatment.

摘要

作者报告了30例关节炎患者关节内及关节周围使用奥古蛋白的治疗结果。在治疗过程开始前、治疗期间及治疗结束时对患者进行了检查,结果显示病情有显著改善。膝关节病患者出现阴性和一般结果的情况更为常见。这一发现可能是由于这些患者关节状况的严重程度所致,不过在这种情况下也更倾向于使用奥古蛋白治疗,因为它可避免医源性损伤。作者还明确指出,将局部麻醉药与奥古蛋白治疗联合使用不会带来任何益处。

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1
[Use of intra- and peri-articular peroxide dismutase in clinical orthopedic practice].[关节内及关节周围过氧化氢酶在临床骨科实践中的应用]
Chir Ital. 1987 Feb;39(1):107-14.
2
Anaphylaxis after intra-articular injection of orgotein. Detection of an IgE-mediated mechanism.关节腔内注射奥古蛋白后发生过敏反应。IgE介导机制的检测。
Allergy. 1987 Jan;42(1):74-6. doi: 10.1111/j.1398-9995.1987.tb02190.x.
3
[Evaluation of the efficacy of orgotein in a series of patients with hydrarthrosis of the knee].[对一系列膝关节积水患者使用奥古蛋白的疗效评估]
Minerva Med. 1986 May 19;77(21):947-51.
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[Intra-articular therapy with superoxide dismutase (orgotein) or cortisone in rheumatoid and arthritic inflammatory finger joint lesions].[超氧化物歧化酶(奥古蛋白)或可的松关节内注射治疗类风湿性和关节炎性手指关节病变]
Handchir Mikrochir Plast Chir. 1984 Mar;16(1):59-63.
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Intrarticular methotrexate in the therapy of rheumatoid arthritis.关节内注射甲氨蝶呤治疗类风湿关节炎。
Recenti Prog Med. 1989 May;80(5):261-2.
6
Intra-articular orgotein in osteoarthritis of the knee: a placebo-controlled efficacy, safety, and dosage comparison.膝关节骨关节炎中关节内注射奥古蛋白:一项安慰剂对照的疗效、安全性及剂量比较研究
Am J Med. 1989 Sep;87(3):295-300. doi: 10.1016/s0002-9343(89)80154-8.
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[The use of superoxide dismutase in articular inflammatory pathology].[超氧化物歧化酶在关节炎症病理学中的应用]
Clin Ter. 1985 Sep 30;114(6):505-8.
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Intra-articular orgotein therapy in osteoarthritis of the knee. A double-blind, placebo-controlled trial.膝关节骨关节炎的关节内奥古蛋白治疗。一项双盲、安慰剂对照试验。
Arzneimittelforschung. 1983;33(8):1199-203.
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[Peroxinorm (Orgotein) in the intra-articular treatment of deforming gonarthroses].[过氧化物酶体激活剂(奥古蛋白)在变形性膝关节炎关节内治疗中的应用]
Fysiatr Revmatol Vestn. 1983 Oct;61(5):270-6.
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[Comparative evaluation of the effectiveness of intra-articular administration of orgotein and hydrocortisone in rheumatoid arthritis].
Ter Arkh. 1988;60(4):118-20.