Aguiar Deize Basílio Dos Santos de, Aguiar Denilson José Marcolino de, Paula Josiane de Fátima Padilha de, Cintho Osvaldo Mitsuyuki
Departamento de Estética e Cosmética, Faculdade Cesumar de Ponta Grossa (Unicesumar), Ponta Grossa 84036-350, PR, Brazil.
Departamento Acadêmico de Mecânica (DAMEC), Universidade Tecnológica Federal do Paraná-UTFPR, Ponta Grossa 84017-220, PR, Brazil.
Polymers (Basel). 2022 Aug 30;14(17):3588. doi: 10.3390/polym14173588.
Mechanical alloying was performed to obtain a composite material with a homogeneous dispersion of silver particles in a poly(vinyl alcohol) (PVA) matrix. Silver is a bactericidal material, and PVA is a widely used biocompatible polymer. Therefore, this mix can lead to a potentially functional biomaterial. This study focuses on the combination of both materials, processed by mechanical alloying, which has a promising application potential. The silver (Ag) used was ultrafine, measuring between 200 and 400 nanometers, produced from silver nitrate (AgNO) redox. The Attritor high-energy, water-cooled ball mill was used to mill PVA for 4 h, at 600 rpm speed rotation and 38:1 power milling. Mechanical alloying was demonstrated to cause particle refinement in PVA with a timespan of 1 h. A slight additional particle decrease occurred for long-time milling. A milling time of 4 h was used to disperse the silver particles in the polymer matrix homogeneously. Hot pressing films were produced from the obtained dispersion powders. The microstructural features were studied using several material characterization techniques. Antimicrobial Susceptibility Tests (AST), conducted in an in-vitro assay, showed a hydrophilic character of the films and a protection against bacterial growth, making the process a promising path for the production of surface protective polymeric films.
采用机械合金化法制备了一种复合材料，其中银颗粒均匀分散在聚乙烯醇（PVA）基体中。银是一种杀菌材料，而PVA是一种广泛使用的生物相容性聚合物。因此，这种混合物可形成一种具有潜在功能的生物材料。本研究聚焦于通过机械合金化加工的这两种材料的组合，其具有广阔的应用潜力。所使用的银（Ag）为超细银，粒径在200至400纳米之间，由硝酸银（AgNO）氧化还原制得。使用高能水冷Attritor球磨机，以600转/分钟的转速和38:1的球料比，对PVA进行4小时的球磨。结果表明，机械合金化可在1小时内使PVA颗粒细化。长时间球磨会使颗粒略有进一步减少。采用4小时的球磨时间，以使银颗粒均匀分散在聚合物基体中。由所得的分散粉末制备热压薄膜。使用多种材料表征技术研究了微观结构特征。在体外试验中进行的抗菌药敏试验（AST）表明，薄膜具有亲水性且能防止细菌生长，这使得该工艺成为生产表面保护性聚合物薄膜的一条有前景的途径。
