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枸橼酸坦度螺酮联合绘画疗法对焦虑症患者服药依从性及睡眠质量影响的临床分析

Clinical Analysis on the Effects of Tandospirone Citrate Assisted by Drawing Therapy on Medication Compliance and Sleep Quality in Patients with Anxiety Disorders.

作者信息

Hou Jichong, Zhang Ruifang

机构信息

The Fourth Department of Psychiatry, Hengshui Seventh People's Hospital, Hengshui 053000, Hebei, China.

Department of Radiotherapy, Hengshui People's Hospital, Hengshui 053000, Hebei, China.

出版信息

Emerg Med Int. 2022 Aug 30;2022:9295627. doi: 10.1155/2022/9295627. eCollection 2022.

Abstract

OBJECTIVE

To explore the clinical effects of tandospirone citrate assisted by drawing therapy (DT) on medication compliance and sleep quality in patients with anxiety disorders.

METHODS

A total of 128 patients with anxiety disorders treated in the hospital were enrolled between January 2020 and January 2022. According to the random number table method, they were divided into the observation group ( = 64) and the control group ( = 64). The control group was treated with tandospirone citrate, while the observation group was additionally treated with DT. The clinical curative effect and medication compliance after treatment, scores of Hamilton Anxiety Scale (HAMA), Pittsburgh Sleep Quality Index (PSQI), and the World Health Organization's Quality of Life Questionnaire-Brief Version (WHOQOL-BREF) before and after treatment were compared between the two groups. The occurrence of adverse reactions during treatment was recorded.

RESULTS

After treatment, the total response rate in the observation group was higher than that in the control group (96.88% 86.94%) ( < 0.05). After treatment, scores of HAMA and PSQI in both groups were decreased, which were lower in the observation group than in the control group ( < 0.05). After treatment, medication compliance in the observation group was higher than that in the control group ( < 0.05). After treatment, scores of environmental factors, social relations, physiological function, and psychological status in both groups were increased, which were higher in the observation group than in the control group ( < 0.05). During treatment, there was no significant difference in the incidence of adverse reactions between the two groups ( > 0.05).

CONCLUSION

DT-assisted tandospirone citrate can effectively improve the clinical symptoms of patients with anxiety disorders, improve medication compliance, sleep quality, and quality of life, and have a certain degree of safety.

摘要

目的

探讨绘画疗法(DT)辅助坦度螺酮治疗焦虑症患者对药物依从性和睡眠质量的临床效果。

方法

选取2020年1月至2022年1月在我院治疗的128例焦虑症患者,采用随机数字表法分为观察组(n = 64)和对照组(n = 64)。对照组采用坦度螺酮治疗,观察组在对照组基础上联合DT治疗。比较两组治疗后的临床疗效、药物依从性,以及治疗前后汉密尔顿焦虑量表(HAMA)评分、匹兹堡睡眠质量指数(PSQI)评分和世界卫生组织生活质量简表(WHOQOL - BREF)评分。记录治疗期间不良反应的发生情况。

结果

治疗后,观察组总有效率高于对照组(96.88% 对86.94%)(P < 0.05)。治疗后,两组HAMA和PSQI评分均降低,且观察组低于对照组(P < 0.05)。治疗后,观察组药物依从性高于对照组(P < 0.05)。治疗后,两组环境领域、社会关系、生理功能和心理状态评分均升高,且观察组高于对照组(P < 0.05)。治疗期间,两组不良反应发生率比较,差异无统计学意义(P > 0.05)。

结论

DT辅助坦度螺酮可有效改善焦虑症患者的临床症状,提高药物依从性、睡眠质量和生活质量,且具有一定安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08a8/9448592/90df52b73777/EMI2022-9295627.002.jpg

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