Morris M J, Pilowsky P M, Minson J B, West M J, Chalmers J P
Clin Exp Pharmacol Physiol. 1987 Feb;14(2):127-32. doi: 10.1111/j.1440-1681.1987.tb00966.x.
Microinjections of kainic acid were made into the pressor area of the rostral ventrolateral medulla oblongata of anaesthetized rabbits, in the region of the C1 adrenaline-containing neurons. Over the 65 min following the microinjection, there was a significant increase in blood pressure, as well as an increase in the release of neuropeptide Y-like immunoreactivity into the spinal subarachnoid space. These data provide evidence for a functional bulbospinal neuropeptide Y-containing projection which may be responsible for mediating the pressor effects of stimulation of the rostral ventrolateral medulla.
将海藻酸微量注射到麻醉兔延髓头端腹外侧加压区含C1肾上腺素能神经元的区域。在微量注射后的65分钟内，血压显著升高，同时神经肽Y样免疫反应性物质向脊髓蛛网膜下腔的释放也增加。这些数据为一种功能性的含延髓-脊髓神经肽Y的投射提供了证据，该投射可能介导了延髓头端腹外侧刺激的升压效应。
