Yap Yi Ting, Gouwanda Darwin, Gopalai Alpha A, Chong Yu Zheng
School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor 47500, Malaysia.
Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Sungai Long, Bandar Sungai Long, Selangor 43000, Malaysia.
J Biomech Eng. 2023 Feb 1;145(2). doi: 10.1115/1.4055564.
Musculoskeletal modeling and simulation have been an emerging trend in human gait analysis. It allows the user to isolate certain biomechanical conditions and elucidate the dynamics of joints and muscles. This study used an open-source musculoskeletal modeling and simulation tool, opensim to investigate the biomechanical effect of knee brace. It collected gait data from thirty-eight participants and examined the gait spatio-temporal parameters, joint angles, and joint moments. Static optimization was performed to estimate the lower extremity muscle force. Statistical analysis was conducted to identify the difference between normal and braced gaits. The results demonstrated the feasibility of this method to investigate the interaction and coordination of lower extremity joints and muscles. The knee brace constrained the range of the motion of the knee during walking. It also changed the walking speed, step length, and stance-to-swing ratio. Several significant differences were found in the joint moments and muscle forces of the rectus femoris, gastrocnemius, soleus and tibialis anterior. Musculoskeletal modeling and simulation tool offers a less invasive and practical alternative to analyze human motion. It also provides a means to investigate the effect of medical devices such as knee brace, which can be potentially beneficial for the future design and development of such devices and for the derivation of future rehabilitation treatment to improve patient's gait.
肌肉骨骼建模与模拟已成为人体步态分析中的一个新兴趋势。它使使用者能够分离出特定的生物力学状况，并阐明关节和肌肉的动力学。本研究使用了一个开源的肌肉骨骼建模与模拟工具OpenSim来研究膝关节支具的生物力学效应。它收集了38名参与者的步态数据，并检查了步态时空参数、关节角度和关节力矩。进行静态优化以估计下肢肌肉力量。进行统计分析以确定正常步态和佩戴支具步态之间的差异。结果证明了该方法用于研究下肢关节和肌肉的相互作用与协调的可行性。膝关节支具在行走过程中限制了膝关节的运动范围。它还改变了步行速度、步长和站立与摆动比例。在股直肌、腓肠肌、比目鱼肌和胫骨前肌的关节力矩和肌肉力量方面发现了几个显著差异。肌肉骨骼建模与模拟工具为分析人体运动提供了一种侵入性较小且实用的替代方法。它还提供了一种手段来研究诸如膝关节支具等医疗设备的效果，这对于此类设备未来的设计和开发以及推导未来改善患者步态的康复治疗可能具有潜在益处。
