School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Selangor Darul Ehsan, Malaysia.
Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Selangor Darul Ehsan, Malaysia.
Med Biol Eng Comput. 2021 Mar;59(3):711-720. doi: 10.1007/s11517-021-02337-7. Epub 2021 Feb 24.
Asymmetrical stiff knee gait is a mechanical pathology that can disrupt lower extremity muscle coordination. A better understanding of this condition can help identify potential complications. This study proposes the use of dynamic musculoskeletal modelling simulation to investigate the effect of induced mechanical perturbation on the kneeand to examine the muscle behaviour without invasive technique. Thirty-eight healthy participants were recruited. Asymmetrical gait was simulated using knee brace. Knee joint angle, joint moment and knee flexor and extensor muscle forces were computed using OpenSim. Differences inmuscle force between normal and abnormal conditions were investigated using ANOVA and Tukey-Kramer multiple comparison test.The results revealed that braced knee experienced limited range of motion with smaller flexion moment occuring at late swing phase. Significant differences were found in all flexormuscle forces and in several extensor muscle forces (p<0.05). Normal knee produced larger flexor muscle force than braced knee. Braced knee generated the largest extensor muscle force at early swing phase. In summary, musculoskeletal modelling simulation can be a computational tool to map and detect the differences between normal and asymmetrical gaits.
不对称僵硬膝步态是一种机械病理学，可破坏下肢肌肉协调。更好地了解这种情况有助于识别潜在的并发症。本研究提出使用动态肌肉骨骼建模模拟来研究诱导的机械干扰对膝关节的影响，并在不使用侵入性技术的情况下检查肌肉行为。 招募了 38 名健康参与者。使用膝关节支具模拟不对称步态。使用 OpenSim 计算膝关节角度、关节力矩以及膝关节屈肌和伸肌的肌肉力。使用 ANOVA 和 Tukey-Kramer 多重比较检验研究正常和异常情况下肌肉力的差异。 结果表明，支具固定的膝关节运动范围有限，在后期摆动阶段发生较小的屈曲力矩。所有屈肌力和几个伸肌力都存在显著差异（p<0.05）。正常膝关节产生的屈肌力大于支具固定的膝关节。支具固定的膝关节在早期摆动阶段产生最大的伸肌力。总之，肌肉骨骼建模模拟可以成为一种计算工具，用于绘制和检测正常步态和不对称步态之间的差异。
