Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.
Department of General Pediatrics, Vanderbilt University Medical Center. One Magnolia Circle, Nashville, Tennessee, USA.
Autism Res. 2022 Nov;15(11):2126-2137. doi: 10.1002/aur.2812. Epub 2022 Sep 9.
Autistic individuals are at an increased risk for both sleep disturbances and depression. While studies in the general population and in autistic adults have drawn general links between sleep disturbances and mental health, few studies have examined the extent to which specific sleep problems may be implicated in the extremely high rates of depression among autistic adults. This study aimed to describe the patterns of sleep disturbances in autistic young adults, and their associations with depressive symptoms while controlling for relevant demographic factors. A sample of 304 legally independent adults (age 18-35 years old) with a childhood diagnosis of autism spectrum disorder self-reported on their average sleep behaviors during the past week and depressive symptoms on the Beck Depressive Inventory-II. A significant proportion (86.01%) of autistic young adults experienced at least one of the primary sleep disturbances of interest, including short total sleep time (39.59%), poor sleep efficiency (60.07%), and delayed sleep phase (36.18%). Additionally, lower sleep efficiency and delayed sleep phase were both associated with higher depressive symptoms. The associations between sleep and depressive symptoms identified in our study suggest that sleep treatments may hold potential for ameliorating depressive symptoms in autistic adults who also experience sleep problems. Further research using daily sleep diaries and objective measures of sleep behaviors, as well as longitudinal studies, are needed to understand how changes in sleep may relate to changes in depressive symptoms in autistic adults.
自闭症个体存在睡眠障碍和抑郁的风险增加。虽然在普通人群和自闭症成年人中的研究已经得出睡眠障碍与心理健康之间存在普遍联系,但很少有研究探讨特定的睡眠问题在自闭症成年人中极高的抑郁率中可能涉及到的程度。本研究旨在描述自闭症青年成年人的睡眠障碍模式,并在控制相关人口统计学因素的情况下,研究其与抑郁症状的关联。本研究的样本由 304 名具有自闭症谱系障碍的成年个体组成,他们在过去一周内平均报告了自己的睡眠行为和贝克抑郁量表二的抑郁症状。相当比例(86.01%)的自闭症青年成年人经历了至少一种主要的睡眠障碍,包括总睡眠时间短(39.59%)、睡眠效率低(60.07%)和睡眠时相延迟(36.18%)。此外,睡眠效率较低和睡眠时相延迟都与更高的抑郁症状相关。本研究中发现的睡眠与抑郁症状之间的关联表明,睡眠治疗可能有潜力改善同时存在睡眠问题的自闭症成年人的抑郁症状。需要使用每日睡眠日记和客观的睡眠行为测量以及纵向研究来进一步研究睡眠的变化如何与自闭症成年人的抑郁症状变化相关。