呋喃妥因的代谢活化——对致癌作用的可能影响。 - Suppr

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Metabolic activation of nitrofurantoin--possible implications for carcinogenesis.

作者信息

Boyd M R, Stiko A W, Sasame H A

出版信息

Biochem Pharmacol. 1979 Mar 1;28(5):601-6. doi: 10.1016/0006-2952(79)90142-4.

DOI:10.1016/0006-2952(79)90142-4

PMID:36083

Abstract

摘要

相似文献

Metabolic activation of nitrofurantoin--possible implications for carcinogenesis.呋喃妥因的代谢活化——对致癌作用的可能影响。

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The role of active metabolites in drug toxicity.活性代谢物在药物毒性中的作用。

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Nitrofurantoin cytotoxicity. In vitro assessment of risk based on glutathione metabolism.呋喃妥因细胞毒性。基于谷胱甘肽代谢的体外风险评估。

J Clin Invest. 1981 Jan;67(1):37-41. doi: 10.1172/JCI110030.

Reductive and oxidative metabolism of nitrofurantoin in rat liver.呋喃妥因在大鼠肝脏中的还原代谢和氧化代谢。

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Cancer Chemother Pharmacol. 1986;16(1):9-14. doi: 10.1007/BF00255279.

CB 1954 revisited. I. Disposition kinetics and metabolism.重访CB 1954。I. 处置动力学与代谢。

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Evidence for the involvement of a nitrenium ion in the covalent binding of nitrofurazone to DNA.关于硝呋腙与DNA共价结合中氮烯离子参与的证据。

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An assessment of the role of redox cycling in mediating the toxicity of paraquat and nitrofurantoin.对氧化还原循环在介导百草枯和呋喃妥因毒性中作用的评估。

Environ Health Perspect. 1990 Apr;85:113-7. doi: 10.1289/ehp.85-1568326.

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