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双侧同步结膜黏液瘤及文献复习。

Bilateral synchronous conjunctival myxoma and review of the literature.

机构信息

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

Hong Kong Eye Hospital, Hong Kong, China.

出版信息

Eur J Ophthalmol. 2023 Sep;33(5):NP130-NP136. doi: 10.1177/11206721221124665. Epub 2022 Sep 9.

Abstract

PURPOSE

The purpose of this study was to report the clinicopathological features and management of the first case of bilateral synchronous conjunctival myxoma.

METHODS

This study was a case report and literature review.

RESULTS

A 66-year-old Chinese male with past ocular history of uncomplicated bilateral phacoemulsification and intraocular lens (IOLs) 3 years ago prior to presentation presented with bilateral red and swollen conjunctiva for over a year. On examination his corrected distance visual acuity (CDVA) was 25/20 in the right eye 20/20 in the left eye. Slit lamp examination revealed swollen temporal conjunctiva bilaterally which appeared as painless, well-circumscribed, salmon-pink, fleshy patches. The lesion in the right eye was subsequently excised, followed by excision of the lesion in the left eye at 3-week interval. Microscopically, histopathological examination of both excised specimens revealed hypocellular conjunctival mucosa covered by non-dysplastic epithelium, with presence of myxoid degeneration in the subepithelial stroma and immunostaining findings consistent with conjunctival myxoma. At his latest follow-up at 24 months, there were no recurrences of the conjunctival masses and the CDVA was the same as preoperatively.

摘要

目的

本研究旨在报告首例双侧结膜黏液瘤的临床病理特征和治疗方法。

方法

本研究为病例报告和文献复习。

结果

一名 66 岁的中国男性,既往眼部史为 3 年前双侧超声乳化白内障吸除术和人工晶状体(IOL)植入术,无复杂病史。此次就诊前 1 年双侧出现结膜红肿。检查时,他的矫正远视力(CDVA)右眼为 25/20,左眼为 20/20。裂隙灯检查显示双侧颞侧结膜肿胀,呈无痛性、边界清楚、鲑鱼粉红色、肉质斑块。右眼病变随后被切除,3 周后左眼病变也被切除。显微镜下,对两个切除标本的组织病理学检查显示,复层柱状上皮覆盖的结膜黏膜细胞稀少,上皮下基质存在黏液样变性,免疫组化染色结果与结膜黏液瘤一致。在 24 个月的最新随访中,结膜肿块无复发,CDVA 与术前相同。

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