在尼日利亚一家大型艾滋病毒诊所接受结核病治疗的患者中，坚持治疗的情况。
Retention in Care among Patients Attending a Large HIV Clinic in Nigeria Who Were Treated for Tuberculosis.
机构信息
Department of Medicine, 113092College of Medicine, University of Ibadan, Ibadan, Nigeria.
Department of Community Medicine, 113092College of Medicine, University of Ibadan, Ibadan, Nigeria.
出版信息
J Int Assoc Provid AIDS Care. 2022 Jan-Dec;21:23259582221124826. doi: 10.1177/23259582221124826.
A retrospective study of 2764 patients was conducted at an HIV clinic in Nigeria to evaluate retention in care in patients treated for TB. At 6 and 12 months after commencement of TB treatment, 1842(66.6%) and 1624(58.8%) participants remained in care. Of the 922 and 1140 not in care at 6 and 12 months, 814(88.3%) and 1006(88.2%) respectively were lost to follow-up (LTFU). VL < 1000copies/ml was associated with higher odds of retention in care at 6 and 12 months (OR = 2.351 and 2.393) than VL > 1000 copies/ml. HAART use was associated with high likelihood of being in care at 12 months (OR = 3.980). CD4 counts of 200-350 and >350 cells/mm were associated with increased odds of remaining in care at 12 months compared with CD4 < 200 cells/mm (p = 0.005 and p = 0.001). Targeted interventions such as early HAART and close follow-up for high risk groups are likely to improve retention in care.
在尼日利亚的一家艾滋病毒诊所，对 2764 名患者进行了回顾性研究，以评估接受结核病治疗的患者的护理保留率。在开始结核病治疗后的 6 个月和 12 个月，1842 名（66.6%）和 1624 名（58.8%）参与者仍在接受护理。在 6 个月和 12 个月未接受护理的 922 名和 1140 名患者中，分别有 814 名（88.3%）和 1006 名（88.2%）因失访而失去随访（LTFU）。病毒载量（VL）<1000 拷贝/ml 与 6 个月和 12 个月时保留护理的可能性更高相关（OR=2.351 和 2.393），而 VL>1000 拷贝/ml 则较低。在 12 个月时，使用高效抗逆转录病毒治疗（HAART）与较高的护理可能性相关（OR=3.980）。与 CD4<200 个细胞/mm 相比，CD4 计数为 200-350 和>350 个细胞/mm 与 12 个月时保持护理的可能性增加相关（p=0.005 和 p=0.001）。针对高危人群的早期 HAART 和密切随访等针对性干预措施可能会提高护理保留率。
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