Department of Cardiology, Selcuk University, Faculty of Medicine, Ardıçlı, No:313, 42250 Selçuklu/Konya, Turkey.
Department of Anesthesiology and Intensive Care, Selcuk University, Faculty of Medicine, Ardıçlı, No:313, 42250 Selçuklu/Konya Konya, Turkey.
Heart Lung. 2023 Jan-Feb;57:75-79. doi: 10.1016/j.hrtlng.2022.08.023. Epub 2022 Aug 30.
Pulmonary hypertension is a significant complication of COVID-19, but follow-up data on pulmonary artery pressure after recovery from COVID-19 are limited.
To investigate pulmonary artery pressure and heart dimensions in post-COVID-19 patients without a history of significant cardiac pathology.
Data for 91 eligible adult patients were subjected to 2 analyses. First, patients were grouped according to where they received COVID-19 treatment: the ICU, COVID-19 ward, or outpatient clinic. Second, the severity of COVID-19 was grouped as no pulmonary involvement, non-severe pulmonary involvement, or severe pulmonary involvement based on thoracic computed tomography scores. Heart dimensions were measured and pulmonary artery pressure was estimated using transthoracic echocardiography. The correlation between transthoracic echocardiography findings and COVID-19 severity was assessed.
Pulmonary artery pressure and right-heart dimensions were significantly elevated in the post-COVID-19 patients without a history of risk factors for pulmonary hypertension that presented to the cardiology outpatient clinic with cardiac complaints. Both of these findings were correlated with the severity of COVID-19 and the extent of lung involvement based on thoracic computed tomography.
The present findings confirm that increases in systolic pulmonary artery pressure and right ventricular dimensions persist 2-3 months after recovery from COVID-19 in patients without a history of risk factor for pulmonary hypertension. Furthermore, the increase in pulmonary artery pressure and right ventricular dimensions correlate with the severity of COVID-19 and the extent of lung involvement based on thoracic computed tomography.
肺动脉高压是 COVID-19 的一个重要并发症，但 COVID-19 康复后肺动脉压的随访数据有限。
调查无重大心脏病理病史的 COVID-19 后患者的肺动脉压和心脏大小。
对 91 名符合条件的成年患者的数据进行了 2 项分析。首先，根据患者接受 COVID-19 治疗的地点将患者分为 ICU、COVID-19 病房或门诊。其次，根据胸部 CT 评分将 COVID-19 的严重程度分为无肺部受累、非严重肺部受累或严重肺部受累。使用经胸超声心动图测量心脏大小并估算肺动脉压。评估经胸超声心动图结果与 COVID-19 严重程度之间的相关性。
在因心脏不适就诊心内科门诊、无肺动脉高压危险因素的 COVID-19 后患者中，肺动脉压和右心尺寸明显升高。这两种发现均与 COVID-19 的严重程度以及基于胸部 CT 的肺受累程度相关。
本研究结果证实，在无肺动脉高压危险因素的 COVID-19 患者中，从 COVID-19 康复后 2-3 个月，收缩期肺动脉压和右心室尺寸持续升高。此外，肺动脉压和右心室尺寸的增加与 COVID-19 的严重程度以及基于胸部 CT 的肺受累程度相关。
