State Key Laboratory of Pollution Control and Resources Reuse, Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
J Hazard Mater. 2023 Jan 5;441:129890. doi: 10.1016/j.jhazmat.2022.129890. Epub 2022 Sep 5.
Gold nanoclusters (Au NCs) with luminescence property are emerging as promising candidates in fluorescent methods for monitoring contaminants, but low luminescence efficiency hampers their extensive applications. Herein, GSH-Au NCs@ZIF-8 was designed by encapsulating GSH-Au NCs with AIE effect into metal-organic frameworks, achieving high luminescence efficiency and good stability through the confinement effect of ZIF-8. Accordingly, a fluorescent sensing platform was constructed for the sensitive detection of copper ions (Cu) and organophosphorus pesticides (OPs). Firstly, the as-prepared GSH-Au NCs@ZIF-8 could strongly accumulate Cu due to the adsorption property of MOFs, accompanied by a significant fluorescence quenching effect with a low detection limit of 0.016 μM for Cu. Besides, thiocholine (Tch), the hydrolysis product of acetylthiocholine (ATch) by acetylcholinesterase (AchE), could coordinate with Cu by sulfhydryl groups (-SH), leading to a significant fluorescence recovery, which was further used for the quantification of OPs owing to its inhibition to AChE activity. Furthermore, a hydrogel sensor was explored to accomplish equipment-free, visual, and quantitative monitoring of Cu and OPs by a smartphone sensing platform. Overall, this work provides an effective and universal strategy for enhancing the luminescence efficiency and stability of Au NCs, which would greatly promote their applications in contaminants monitoring.
具有发光性能的金纳米团簇 (Au NCs) 作为荧光方法监测污染物的有前途的候选物而出现，但发光效率低阻碍了它们的广泛应用。在此，通过将具有聚集诱导发光 (AIE) 效应的 GSH-Au NCs 封装到金属-有机骨架中，设计了 GSH-Au NCs@ZIF-8，通过 ZIF-8 的限制效应实现了高发光效率和良好的稳定性。因此，构建了一个荧光传感平台，用于灵敏检测铜离子 (Cu) 和有机磷农药 (OPs)。首先，由于 MOFs 的吸附特性，所制备的 GSH-Au NCs@ZIF-8 可以强烈积累 Cu，同时伴随着荧光猝灭效应，Cu 的检测限低至 0.016 μM。此外，硫代胆碱 (Tch) 是乙酰胆碱酯酶 (AchE) 水解乙酰硫代胆碱 (ATch) 的产物，可通过巯基 (-SH) 与 Cu 配位，导致显著的荧光恢复，这进一步用于定量检测 OPs，因为它抑制 AchE 活性。此外，通过智能手机传感平台，探索了水凝胶传感器，用于实现无设备、可视化和定量监测 Cu 和 OPs。总的来说，这项工作为提高 Au NCs 的发光效率和稳定性提供了一种有效且通用的策略，这将极大地促进它们在污染物监测中的应用。
