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印度女性癌症:来自国家癌症登记计划的发病率、趋势及其临床范围

Women cancers in India: Incidence, trends and their clinical extent from the National Cancer Registry Programme.

作者信息

Chaturvedi Meesha, Sathishkumar Krishnan, Lakshminarayana Sudarshan Kondalli, Nath Anita, Das Priyanka, Mathur Prashant

机构信息

National Centre for Disease Informatics and Research, Indian Council of Medical Research, National Cancer Registry Programme, Nirmal Bhawan, ICMR Complex Poojanhalli Road, Off NH-7, Adjacent to Trumpet Flyover of BIAL, Kannamangala Post, Bangalore 562 110, India.

National Centre for Disease Informatics and Research, Indian Council of Medical Research, National Cancer Registry Programme, Nirmal Bhawan, ICMR Complex Poojanhalli Road, Off NH-7, Adjacent to Trumpet Flyover of BIAL, Kannamangala Post, Bangalore 562 110, India.

出版信息

Cancer Epidemiol. 2022 Oct;80:102248. doi: 10.1016/j.canep.2022.102248. Epub 2022 Sep 6.

Abstract

BACKGROUND

To provide a comprehensive assessment of women cancer in India utilizing the systematically collected data on all cancers by the National Cancer Registry Programme (NCRP).

METHODS

The study examined 10,2287 cancer cases among women cancers providing cancer burden for major anatomical sites. Aggregated data of 28 PBCRs and 58 HBCRs under NCRP for 2012-16 was analysed for incidence rates, trends, cumulative risk of developing cancer, stage at detection and treatments offered.

RESULTS

Study results have found region -wide variation of women cancers by indicating highest proportions in western followed by southern region of India. North-Eastern region had lowest proportion. It was observed that breast is highest ranking cancer in most registry areas of urban agglomerations of country while cancer cervix was leading site in registries of rural areas like Barshi (15.3) and Osmanabad &Beed (13.1). States of Mizoram (23.2) and Tripura (9.5) along with Pasighat, Cachar and Nagaland. Median age of occurrence for women for these anatomical sites ranged from 45 to 60 years of age. For cancer breast, cervix and ovary -most cases were detected with regional spread. These findings were different for cancer corpus uteri where registries have reported higher proportions (49.3 %) of localized stage at detection. Loco regional cancers had higher proportions of multimodality treatments.

CONCLUSION

Study provides a foundation for assessing the status of women cancers in the country. Variations between geographies would guide appropriate support for action to strengthen efforts to improve cancer prevention and control in underserved areas of the country. This would facilitate advocacy for better investments and research on women cancers.

摘要

背景

利用国家癌症登记计划(NCRP)系统收集的所有癌症数据,对印度女性癌症进行全面评估。

方法

该研究调查了102287例女性癌症病例,提供了主要解剖部位的癌症负担情况。分析了NCRP下28个基于人群的癌症登记处(PBCR)和58个医院癌症登记处(HBCR)2012 - 2016年的汇总数据,以了解发病率、趋势、患癌累积风险、检测阶段及所提供的治疗情况。

结果

研究结果发现,女性癌症在各地区存在差异,西部地区比例最高,其次是印度南部地区。东北地区比例最低。据观察,在该国大多数城市群的登记地区,乳腺癌是排名最高的癌症,而在农村地区的登记处,如巴尔希(15.3)、奥斯曼阿巴德和比德(13.1),子宫颈癌是主要部位。米佐拉姆邦(23.2)和特里普拉邦(9.5)以及帕西格哈特、卡恰尔和那加兰邦也是如此。这些解剖部位女性发病的中位年龄在45至60岁之间。对于乳腺癌、子宫颈癌和卵巢癌,大多数病例在检测时已出现区域扩散。子宫体癌的情况有所不同,登记处报告其检测时局限期的比例较高(49.3%)。局部区域性癌症接受多模式治疗的比例较高。

结论

该研究为评估该国女性癌症状况提供了基础。地域差异将指导采取适当的支持行动,以加强在该国服务不足地区的癌症预防和控制工作。这将有助于推动对女性癌症进行更好的投资和研究。

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