Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:4974-4977. doi: 10.1109/EMBC48229.2022.9871915.
Microwave ablation (MWA) is a clinically widespread minimally invasive treatment method for lung tumors. Preoperative planning plays a vital role in MWA therapy. However, previous planning methods are far from satisfactory in clinical practice because they only one-sidedly consider the surgical path or energy parameters of an MWA surgery. In this paper, we propose a novel planning model with a computational model of thermal damage to integrally optimize both the surgical path and energy parameters. To ensure the model can be solved in a reasonable time, we elaborate a search space reducing strategy based on clinical constraints. Simulation and ex vivo experimental results were compared with an average mean absolute error of 0.82 K and an average root mean square error of 1.01 K. Our planning model was evaluated on clinical data, and the experimental results demonstrate the effectiveness of our model.
微波消融（MWA）是一种广泛应用于肺部肿瘤的临床微创治疗方法。术前规划在 MWA 治疗中起着至关重要的作用。然而，由于之前的规划方法仅片面考虑 MWA 手术的手术路径或能量参数，因此在临床实践中远远不能令人满意。在本文中，我们提出了一种新的规划模型，该模型采用热损伤计算模型来综合优化手术路径和能量参数。为了确保模型能够在合理的时间内求解，我们基于临床约束详细阐述了一种搜索空间减小策略。模拟和离体实验结果的平均绝对误差为 0.82 K，平均均方根误差为 1.01 K。我们的规划模型在临床数据上进行了评估，实验结果证明了我们模型的有效性。
