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体形成像评估肝脏脂肪。

Liver Fat Assessment with Body Shape.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:2716-2719. doi: 10.1109/EMBC48229.2022.9871321.

Abstract

Hepatic steatosis has become a serious health concern among the general population, but especially for those who are obese. Liver fat can increase the risk of cirrhosis and even liver cancer. Current standard methods to assess hepatic steatosis, such as liver biopsy and CT/MR imaging techniques, are expensive and/or may have associated risks to health. In this paper, we use body shapes to assess hepatic steatosis using both traditional linear regression models and a deep neural network. We apply our models to a medical dataset and evaluate the approaches for both regression and classification. We compare the performance of several models via popular evaluation metrics. The experimental results indicate that our proposed neural network outperforms the vanilla linear regression model by 22.37% in RMSE and the accuracy by 18%. The R-squared value of the neural model is more than 0.72 and the accuracy reaches 78%. Hence, the body shape features can provide an additional accurate and affordable choice to monitor the degree of the patient's liver fat. Clinical relevance - This paper presents a low cost and convenient approach to predict liver fat percentage using body shapes. This approach will not replace the gold standard for assessing hepatic steatosis. However, with the wide availability for depth cameras (including on smartphones), the approach promises to provide another modality that can be deployed widely in clinical setting as well for home use for telehealth.

摘要

肝脂肪变性已成为普通人群,尤其是肥胖人群的严重健康问题。肝脏脂肪会增加肝硬化甚至肝癌的风险。目前评估肝脂肪变性的标准方法,如肝活检和 CT/MR 成像技术,既昂贵又/或可能对健康有相关风险。在本文中,我们使用体型,通过传统的线性回归模型和深度神经网络来评估肝脂肪变性。我们将模型应用于医学数据集,并评估回归和分类的方法。我们通过常用的评估指标比较了几种模型的性能。实验结果表明,我们提出的神经网络在 RMSE 上比普通线性回归模型高出 22.37%,准确率高出 18%。神经模型的 R 平方值超过 0.72,准确率达到 78%。因此,体型特征可以为监测患者肝脏脂肪程度提供一种额外的准确和经济实惠的选择。临床相关性-本文提出了一种使用体型预测肝脂肪百分比的低成本、便捷方法。这种方法不会替代评估肝脂肪变性的金标准。然而,随着深度相机(包括智能手机上的相机)的广泛应用,这种方法有望提供另一种可广泛应用于临床环境以及远程医疗的家庭使用的模式。

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本文引用的文献

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S2FLNet: Hepatic steatosis detection network with body shape.S2FLNet:具有身体形状的肝脂肪变性检测网络。
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Nonalcoholic Steatohepatitis: A Review.非酒精性脂肪性肝炎:综述。
JAMA. 2020 Mar 24;323(12):1175-1183. doi: 10.1001/jama.2020.2298.
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Waist circumference is associated with liver fat in black and white adolescents.腰围与黑人和白人青少年的肝脂肪有关。
Appl Physiol Nutr Metab. 2017 Aug;42(8):829-833. doi: 10.1139/apnm-2016-0410. Epub 2017 Mar 23.

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