Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:1630-1633. doi: 10.1109/EMBC48229.2022.9871392.
Tinnitus is the perception of sound when no actual external noise is present. Tinnitus is highly prevalent, with more than 1 in 7 adults in the EU having tinnitus, and it causes negative effects on quality of life for many individuals. However, there is currently no cure for tinnitus and its pathophysiology and genesis are unknown. Auditory evoked potentials (AEPs) provide a non-invasive means by which the electrical signals evoked by the brain can be recorded, and constitute a useful indicator for the evaluation of auditory disorders such as tinnitus and hearing loss. The present study analyzed a total of 98 auditory middle evoked potential (AMLR) waveforms, a subtype of AEPs, from 49 participants with subjective tinnitus, attempting to identify differences in AMLR parameters between sufferers with and without tinnitus distress. The waveforms were divided into three categories according to the ear's hearing level, and comparisons were made between sufferers in the same hearing level category. The results of the analysis indicated some statistically significant differences in AMLR latencies and amplitudes between the compared groups. Clinical Relevance- Identification of the electro-physiological profile of subjective tinnitus sufferers based on the distress manifested by tinnitus using AMLRs.
耳鸣是指在没有实际外部噪音的情况下感知到的声音。耳鸣的发病率很高，欧盟超过 1/7 的成年人患有耳鸣，它给许多人带来了生活质量的负面影响。然而，目前尚无治愈耳鸣的方法，其病理生理学和发生机制尚不清楚。听觉诱发电位 (AEPs) 提供了一种非侵入性的方法，可以记录大脑产生的电信号，是评估耳鸣和听力损失等听觉障碍的有用指标。本研究共分析了 49 名主观耳鸣患者的 98 个听觉中潜伏期诱发电位 (AMLR) 波形，这是 AEPs 的一个亚型，试图确定耳鸣困扰和不困扰的 AMLR 参数之间的差异。根据耳朵的听力水平将波形分为三类，并对同一听力水平类别内的患者进行比较。分析结果表明，在比较组之间，AMLR 潜伏期和振幅存在一些统计学上显著的差异。临床意义-根据 AMLRs 显示的耳鸣困扰，确定主观耳鸣患者的电生理特征。
