Tiep B L, Lewis M I
Chest. 1987 Aug;92(2):263-72. doi: 10.1378/chest.92.2.263.
The efficacy of long-term oxygen therapy for hypoxemic COPD patients is well established. However, oxygen is expensive and the portability of home oxygen is limited by the weight and bulk of the oxygen source. As a result, there has been a recent surge of interest in creating oxygen-conserving devices and methods. The efficiency of oxygen therapy can be improved over steady flow delivery by focusing oxygen delivery to early inspiration. Three methods for improving oxygen delivery efficiency--transtracheal catheter, reservoir cannula and demand-pulse oxygen delivery--are currently available for patient use. Each has its own set of advantages and disadvantages. By using oxygen conservation methods, the oxygen required to achieve adequate blood oxygenation can be reduced by a factor of 2:1 to 7:1 compared to steady flow. Thus, the cost of oxygen can be substantially reduced while increasing the portability and range of home oxygen therapy.
长期氧疗对低氧慢性阻塞性肺疾病（COPD）患者的疗效已得到充分证实。然而，氧气价格昂贵，且家庭用氧的便携性受到氧源重量和体积的限制。因此，最近人们对开发氧节约装置和方法的兴趣激增。通过将氧气输送集中在吸气早期，与持续气流输送相比，氧疗效率可以得到提高。目前有三种提高氧气输送效率的方法可供患者使用，即经气管导管、储氧插管和按需脉冲式氧气输送。每种方法都有其自身的优缺点。通过使用氧节约方法，与持续气流相比，实现足够血液氧合所需的氧气量可减少2倍至7倍。因此，在提高家庭氧疗的便携性和使用范围的同时，可大幅降低氧气成本。
