Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:2365-2368. doi: 10.1109/EMBC48229.2022.9871641.
Temporal interference (TI) stimulation is a technique in which two high frequency sinusoidal electric fields, oscillating at a slightly different frequency are sent into the brain. The goal is to achieve stimulation at the place where both fields interfere. This study uses a simplified version of the Hodgkin - Huxley model to analyse the different parameters of the TI-waveform and how the neuron reacts to this waveform. In this manner, the underlying mechanism of the reaction of the neuron to a TI -signal is investigated. Clinical relevance- This study shows the importance of the parameter choice of the temporal interference waveform and provides insights into the underlying mechanism of the neuronal response to a beating sine for the application of temporal interference stimulation.
时频干扰（TI）刺激是一种将两个频率略有不同的高频正弦电场送入大脑的技术。其目的是在两个场相互干扰的地方实现刺激。本研究使用简化的 Hodgkin-Huxley 模型来分析 TI 波的不同参数以及神经元对此波形的反应。通过这种方式，研究了神经元对 TI 信号反应的基本机制。临床意义——本研究表明了选择时频干扰波形参数的重要性，并为神经元对正弦波刺激的反应的基本机制提供了深入了解，为时间干扰刺激的应用提供了依据。
