School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital, Taichung, Taiwan.
Medicine (Baltimore). 2022 Sep 9;101(36):e30437. doi: 10.1097/MD.0000000000030437.
To describe the incidence of benign prostatic hyperplasia (BPH) after a diagnosis of carpal tunnel syndrome or trigger finger. We performed a retrospective study on national health registry comparing the incidence of BPH between a cohort of 9720 study patients and a comparison cohort of 38,880 control individuals. The crude hazard ratio (HR) and the adjusted HR were estimated by the univariable and the multivariable Cox proportional hazard model, respectively. The risks of BPH in different age groups and patients with or without comorbidities were also investigated. The cumulative incidence curves were obtained by the Kaplan-Meier method and assessed by the Log-rank test. Compared to the control cohort, patients with carpal tunnel syndrome increased the risk of BPH by 1.36 times (95% confidence intervals [CI] = 1.29, 1.43). Patients only diagnosed with trigger finger raised the risk of BPH by 1.31 times (95% CI = 1.22, 1.40). The HR of BPH for patients with both carpal tunnel syndrome and trigger finger relative to the controls was 1.43 (95% CI = 1.33, 1.54). We concluded that the likelihood of developing BPH was increased in patients with carpal tunnel syndrome or trigger finger.
描述诊断为腕管综合征或扳机指后良性前列腺增生（BPH）的发病率。我们对国家健康登记处进行了一项回顾性研究，将 9720 名研究患者队列和 38880 名对照个体的队列的 BPH 发病率进行比较。分别通过单变量和多变量 Cox 比例风险模型估计了粗危害比（HR）和调整后的 HR。还研究了不同年龄组、有无合并症的患者发生 BPH 的风险。通过 Kaplan-Meier 方法获得累积发病率曲线，并通过 Log-rank 检验进行评估。与对照组相比，患有腕管综合征的患者发生 BPH 的风险增加了 1.36 倍（95%置信区间[CI] = 1.29，1.43）。仅诊断为扳机指的患者发生 BPH 的风险增加了 1.31 倍（95%CI = 1.22，1.40）。与对照组相比，同时患有腕管综合征和扳机指的患者发生 BPH 的 HR 为 1.43（95%CI = 1.33，1.54）。我们得出结论，腕管综合征或扳机指患者发生 BPH 的可能性增加。
