Hu Wei-Syun, Lin Cheng-Li
School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital, Taichung, Taiwan.
Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
J Epidemiol. 2017 Dec;27(12):574-577. doi: 10.1016/j.je.2016.12.015. Epub 2017 Mar 3.
This study was conducted to evaluate the association between hemorrhoid and risk of incident peripheral artery occlusive disease (PAOD).
Using the Taiwanese Longitudinal Health Insurance Database 2000, we compared the incident PAOD risk between the hemorrhoid and the non-hemorrhoid cohorts. Both of these cohorts were followed up from the index date until the date of PAOD diagnosis, withdrawal from the National Health Insurance program, or the end of 2011.
The mean follow-up period was 6.82 (standard deviation [SD], 3.22) and 6.70 (SD, 3.23) years in the hemorrhoid and non-hemorrhoid cohorts, respectively. The plot of the Kaplan-Meier analysis showed that, by the end of the 12-year follow-up period, the cumulative incidence of PAOD was significantly higher for the hemorrhoid cohort than for the non-hemorrhoid cohort (log-rank test: P < 0.001).
A significantly increased PAOD risk in patients with hemorrhoids was found in this nationwide cohort study.
本研究旨在评估痔疮与外周动脉闭塞性疾病（PAOD）发病风险之间的关联。
利用台湾地区2000年纵向健康保险数据库，我们比较了痔疮队列和非痔疮队列中PAOD的发病风险。这两个队列均从索引日期开始随访，直至PAOD诊断日期、退出国民健康保险计划或2011年底。
痔疮队列和非痔疮队列的平均随访期分别为6.82（标准差[SD]，3.22）年和6.70（SD，3.23）年。Kaplan-Meier分析图显示，在12年随访期结束时，痔疮队列中PAOD的累积发病率显著高于非痔疮队列（对数秩检验：P < 0.001）。
在这项全国性队列研究中，发现痔疮患者的PAOD风险显著增加。
