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Curr Allergy Asthma Rep. 2022 Nov;22(11):151-161. doi: 10.1007/s11882-022-01041-2. Epub 2022 Sep 10.
2
Budesonide + formoterol delivered via Spiromax for the management of asthma and COPD: The potential impact on unscheduled healthcare costs of improving inhalation technique compared with Turbuhaler.通过思力华能倍乐装置吸入布地奈德+福莫特罗用于哮喘和慢性阻塞性肺疾病的管理:与都保装置相比,改善吸入技术对非计划医疗费用的潜在影响。
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BMC Pulm Med. 2018 Jun 28;18(1):107. doi: 10.1186/s12890-018-0665-x.
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Real-life association between inhaler technique, patient preference and asthma control in patients with uncontrolled asthma switched to budesonide/formoterol DuoResp® Spiromax® combination.在未控制的哮喘患者中,将布地奈德/福莫特罗 DuoResp® Spiromax® 联合用药转换后,吸入器技术、患者偏好与哮喘控制之间的真实关联。
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Clinical Effectiveness of Budesonide/Formoterol Fumarate Easyhaler for Patients with Poorly Controlled Obstructive Airway Disease: a Real-World Study of Patient-Reported Outcomes.布地奈德/福莫特罗富马酸酯(信必可都保)治疗控制不佳的气道阻塞性疾病患者的临床疗效:患者报告结局的真实世界研究。
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本文引用的文献

1
Real-life association between inhaler technique, patient preference and asthma control in patients with uncontrolled asthma switched to budesonide/formoterol DuoResp® Spiromax® combination.在未控制的哮喘患者中,将布地奈德/福莫特罗 DuoResp® Spiromax® 联合用药转换后,吸入器技术、患者偏好与哮喘控制之间的真实关联。
J Asthma. 2022 Apr;59(4):765-774. doi: 10.1080/02770903.2021.1875482. Epub 2021 Feb 13.
2
Assessment of inhalation errors, training time and patient preference for DuoResp® Spiromax® and Symbicort® Turbuhaler® in patients with asthma and COPD.哮喘和慢性阻塞性肺疾病患者使用都保®思力华®和信必可都保®时吸入错误、训练时间及患者偏好的评估
Eur Clin Respir J. 2020 Oct 18;8(1):1833411. doi: 10.1080/20018525.2020.1833411.
3
Inhaler devices in asthma and COPD patients - a prospective cross-sectional study on inhaler preferences and error rates.哮喘和 COPD 患者的吸入器设备 - 关于吸入器偏好和错误率的前瞻性横断面研究。
BMC Pulm Med. 2020 Aug 20;20(1):222. doi: 10.1186/s12890-020-01246-z.
4
Predictive value of control of COPD for risk of exacerbations: An international, prospective study.COPD 控制对加重风险的预测价值:一项国际前瞻性研究。
Respirology. 2020 Nov;25(11):1136-1143. doi: 10.1111/resp.13811. Epub 2020 Apr 6.
5
Effectiveness and Patient Satisfaction with Budesonide/Formoterol Easyhaler Among Patients with Asthma or COPD Switching from Previous Treatment: a Real-World Study of Patient-Reported Outcomes.布地奈德/福莫特罗易纳器对哮喘或慢性阻塞性肺疾病患者从既往治疗转换过来后的有效性及患者满意度:一项患者报告结局的真实世界研究
Pulm Ther. 2019 Dec;5(2):165-177. doi: 10.1007/s41030-019-0097-7. Epub 2019 Jul 29.
6
The dry powder inhaler features of the Easyhaler that benefit the management of patients.易纳器干粉吸入器的特点有利于患者的管理。
Expert Rev Respir Med. 2020 Apr;14(4):345-351. doi: 10.1080/17476348.2020.1721286. Epub 2020 Feb 4.
7
Understanding Dry Powder Inhalers: Key Technical and Patient Preference Attributes.了解干粉吸入器:关键技术和患者偏好属性。
Adv Ther. 2019 Oct;36(10):2547-2557. doi: 10.1007/s12325-019-01066-6. Epub 2019 Sep 2.
8
DuoResp Spiromax adherence, satisfaction and ease of use: findings from a multi-country observational study in patients with asthma and COPD in Europe (SPRINT).多索布气雾剂的依从性、满意度和使用便捷性:来自欧洲哮喘和 COPD 患者多国观察性研究(SPRINT)的结果。
J Asthma. 2020 Oct;57(10):1110-1118. doi: 10.1080/02770903.2019.1634097. Epub 2019 Jul 11.
9
Use and inhalation technique of inhaled medication in patients with asthma and COPD: data from a randomized controlled trial.哮喘和 COPD 患者吸入药物的使用和吸入技术:一项随机对照试验的数据。
Respir Res. 2018 Dec 3;19(1):237. doi: 10.1186/s12931-018-0936-3.
10
The importance of patient-reported outcomes in clinical trials and strategies for future optimization.患者报告结局在临床试验中的重要性及未来优化策略。
Patient Relat Outcome Meas. 2018 Nov 1;9:353-367. doi: 10.2147/PROM.S156279. eCollection 2018.

患者报告结局和吸入器操作错误在哮喘和 COPD 控制中的作用的叙述性综述。

Narrative Review of the Role of Patient-Reported Outcomes and Inhaler Handling Errors in the Control of Asthma and COPD.

机构信息

Primary Care Physician, Luis Vives Health Center, Alcala de Henares, Madrid, Spain.

Primary Care Physician, Henares Azuqueca Health Center, Guadalajara, Spain.

出版信息

Curr Allergy Asthma Rep. 2022 Nov;22(11):151-161. doi: 10.1007/s11882-022-01041-2. Epub 2022 Sep 10.

DOI:10.1007/s11882-022-01041-2
PMID:36087251
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9532287/
Abstract

PURPOSE OF REVIEW

Asthma and chronic obstructive pulmonary disease (COPD) are chronic respiratory diseases that remain uncontrolled in many patients, despite the wide range of therapeutic options available. This review analyzes the available clinical evidence on 3 budesonide/formoterol DPI devices, Spiromax, Turbuhaler, and Easyhaler, in terms of patient-reported outcomes (PROs), inhaler errors, and asthma and COPD control.

RECENT FINDINGS

The effectiveness of dry powder inhalers (DPI) depends largely on the device and the patient's inhaler technique. Equally important are the patient's perception of the inhaler and adherence. Given the high burden of these diseases, it is important that efforts be made to select the best DPI for each patient and to analyze the impact of these variables to help improve the health and quality of life of our patients. This review provides a comprehensive overview of the present knowledge about PROs, inhaler handling errors, and asthma and COPD control achieved by Spiromax, Turbuhaler, and Easyhaler.

摘要

目的综述

尽管有多种治疗选择,但哮喘和慢性阻塞性肺疾病(COPD)仍然是许多患者无法控制的慢性呼吸道疾病。本综述分析了现有关于布地奈德/福莫特罗三种干粉吸入器(DPI),即 Spiromax、Turbuhaler 和 Easyhaler 的临床证据,内容涉及患者报告的结局(PRO)、吸入器错误以及哮喘和 COPD 的控制情况。

最新发现

干粉吸入器(DPI)的有效性在很大程度上取决于设备和患者的吸入器技术。同样重要的是患者对吸入器的感知和依从性。鉴于这些疾病的负担很重,重要的是要努力为每个患者选择最佳的 DPI,并分析这些变量的影响,以帮助改善我们患者的健康和生活质量。本综述全面概述了 Spiromax、Turbuhaler 和 Easyhaler 在患者报告的结局、吸入器操作错误以及哮喘和 COPD 控制方面的现有知识。