抗氧化剂在预防和治疗噪声性听力损失中的应用。

The Use of Antioxidants in the Prevention and Treatment of Noise-Induced Hearing Loss.

机构信息

Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA.

出版信息

Otolaryngol Clin North Am. 2022 Oct;55(5):983-991. doi: 10.1016/j.otc.2022.06.006. Epub 2022 Sep 7.

DOI:10.1016/j.otc.2022.06.006

PMID:36088150

Abstract

As of today, there are no therapeutic measures for the prevention or treatment of noise-induced hearing loss (NIHL). The current preventative measures, including avoidance and personal protective hearing equipment, do not appear to be sufficient because there is an increasing number of people with NIHL, especially in the adolescent population. Therefore, we must find a therapy that prevents the impact of noise on hearing. Antioxidants are a promising option in preventing the damaging effects of noise by targeting free radicals but further studies are needed to confirm their efficacy in humans.

摘要

截至今日，针对噪声性听力损失（NIHL），尚无预防或治疗措施。目前的预防措施，包括避免和使用个人防护听力设备，似乎并不充分，因为患有 NIHL 的人数不断增加，尤其是在青少年人群中。因此，我们必须找到一种可以预防噪声对听力影响的疗法。抗氧化剂是一种很有前途的选择，它可以通过靶向自由基来预防噪声的破坏性影响，但需要进一步的研究来证实它们在人类中的疗效。