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[食管癌继发食管气管瘘和食管支气管瘘的治疗]

[Treatment of esophagotracheal and esophagobronchial fistulas secondary to carcinoma of the esophagus].

作者信息

Forni E, Zadra F, Lo Monaco G, Spelzini P, Clerico D, Bordoni P

出版信息

Chir Ital. 1984 Oct;36(5):773-84.

PMID:6545138
Abstract

An experience with 16 patients with respiratory tract fistula (RTF) related to carcinoma of the esophagus is presented. The malignant fistula was present at the time of initial presentation and/or before any therapeutic intervention in 11 patients, and developed either during or following a course of radiation therapy in 5 patients. Bronchoscopy examination in 8 patients prior to RTF development showed tracheobronchial invasion or impingement in all. The patients were divided in five groups according to the treatment received. One patient received no specific therapy although was fed via nasogastric tube. Three patients had a feeding gastrostomy. Four patients underwent insertion of a Celestin tube. Three patients were submitted to esophageal exclusion with combinations of cervical esophagostomy, feeding gastrostomy and ligation or complete division of the gastroesophageal junction; drainage of the excluded esophagus was provided by a red rubber catheter. Five patients received by-pass operation: four had Kirschner-Ong operation with gastric by-pass placed substernally and distal esophagus anastomosed to a Roux-en-Y jejunal loop; in one patient an isoperistaltic gastric tube brought to the neck substernally was used for esophageal by-pass. These patients had, by far, the best palliative results with complete relief of their respiratory tract symptoms and restoration of the ability to eat and drink. Substernal gastric by-pass of the RTF is therefore advocated if the general conditions of the patient are improved with the institution of parenteral hyperalimentation and antibiotic therapy.

摘要

本文介绍了16例与食管癌相关的呼吸道瘘(RTF)患者的治疗经验。11例患者在初次就诊时和/或在任何治疗干预之前就已存在恶性瘘,5例患者在放疗过程中或放疗后出现瘘。8例患者在RTF发生前进行的支气管镜检查均显示气管支气管受侵或受压。根据接受的治疗方法,将患者分为五组。1例患者未接受特殊治疗,但通过鼻胃管进食。3例患者行胃造瘘术。4例患者插入了Celestin管。3例患者接受了食管旷置术,包括颈段食管造口术、胃造瘘术以及胃食管交界处结扎或完全离断;通过一根红色橡胶导管对旷置的食管进行引流。5例患者接受了旁路手术:4例患者行Kirschner-Ong手术,将胃旁路置于胸骨后,远端食管与Roux-en-Y空肠袢吻合;1例患者使用经胸骨后带至颈部的顺蠕动胃管进行食管旁路。到目前为止,这些患者的姑息治疗效果最佳,呼吸道症状完全缓解,恢复了饮食能力。因此,如果通过肠外营养支持和抗生素治疗改善了患者的一般状况,提倡对RTF行胸骨后胃旁路术。

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