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[自体冷冻保存甲状旁腺组织在永久性术后甲状旁腺功能减退中的再植]

[Replantation of autologous cryopreserved parathyroid tissue in permanent postoperative hypoparathyroidism].

作者信息

Wagner P K, Rothmund M

出版信息

Dtsch Med Wochenschr. 1987 Jul 24;112(30):1160-2. doi: 10.1055/s-2008-1068213.

Abstract

Cryopreserved autologous parathyroid tissue was reimplanted into 16 patients with permanent postoperative hypoparathyroidism. In 13 cases the number of necrotic cells in the thawed cryopreserved tissue was determined histologically and compensated by using a greater amount of tissue particles during re-implantation. These patients had normal transplant functioning after a median period of 6 months. On the other hand, delayed onset of functioning of the autotransplant was seen if the rate of necrotic cells had not been compensated. The results show that re-implantation of autologous cryopreserved parathyroid tissue is a suitable method for treating permanent postoperative hypoparathyroidism. The method should be used as a firmly established part of parathyroid surgery.

摘要

将冷冻保存的自体甲状旁腺组织重新植入16例术后永久性甲状旁腺功能减退患者体内。在13例患者中,通过组织学方法确定解冻后的冷冻保存组织中的坏死细胞数量,并在重新植入时使用更多的组织颗粒进行补偿。这些患者在中位时间6个月后移植功能正常。另一方面,如果坏死细胞的比例没有得到补偿,则会出现自体移植功能延迟出现的情况。结果表明,重新植入冷冻保存的自体甲状旁腺组织是治疗术后永久性甲状旁腺功能减退的一种合适方法。该方法应作为甲状旁腺手术中一个已确立的组成部分使用。

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