Seki K, Kato K, Shima K
Endocrinol Jpn. 1987 Feb;34(1):129-32. doi: 10.1507/endocrj1954.34.129.
The 24-h secretory pattern of GH was evaluated in normal women (n = 4) and hyperprolactinemic-amenorrheic women with pituitary microadenoma (n=6). Serum GH concentrations significantly differed according to the time of day, and there were nocturnal rises in normal women and hyperprolactinemic women. However, episodic fluctuations in serum GH levels were almost absent during the day time in hyperprolactinemic women, and the mean 24-h GH concentration was significantly lower in these women than in normal women. Thus, GH secretion was diminished in hyperprolactinemic women with pituitary microadenoma, though a nocturnal increase in GH secretion continued.
对正常女性（n = 4）和患有垂体微腺瘤的高催乳素血症闭经女性（n = 6）的生长激素（GH）24小时分泌模式进行了评估。血清GH浓度根据一天中的时间显著不同，正常女性和高催乳素血症女性均有夜间升高。然而，高催乳素血症女性白天血清GH水平几乎没有 episodic波动，且这些女性的24小时平均GH浓度显著低于正常女性。因此，患有垂体微腺瘤的高催乳素血症女性的GH分泌减少，尽管GH分泌夜间仍持续增加。
