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外阴皮肤病:一项 5 年的横断面研究。在专门外阴单位的经验。

Vulvar dermatoses: a cross-sectional 5-year study. Experience in a specialized vulvar unit.

机构信息

Dermatology Department, Hospital Viamed Santa Angela de la Cruz, Seville, Spain.

Dermatology Department, Hospital Viamed Santa Angela de la Cruz, Seville, Spain.

出版信息

An Bras Dermatol. 2022 Nov-Dec;97(6):747-756. doi: 10.1016/j.abd.2021.11.006. Epub 2022 Sep 8.

DOI:10.1016/j.abd.2021.11.006
PMID:36089549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9582872/
Abstract

BACKGROUND

Vulvar diseases are common in the general population and have a negative impact on the quality of life.

OBJECTIVES

To describe our experience as dermatologists in the management of vulvar dermatosis consultations.

METHODS

A retrospective observational study was conducted with patients who attended monographic vulvar consultations over a 5-year period. Clinical information was obtained from the patient's charts.

RESULTS

148 women were studied. Their mean age was 43.24 years (standard deviation: 15.15 years), with ages ranging from 4 months to 80 years. 53.4% of patients took between 2 and 5 years to seek medical attention for the first time. The most frequent diagnosis was lichen sclerosus (41.9%), irritative eczema of the vulva (14.9%), and lichen simplex chronicus (10.1%). 83.8% reported anogenital itching, 66.2% pain, and 45.9% dyspareunia. The most frequently prescribed treatment was ultra-potent topical corticosteroids (clobetasol propionate; 41.2%). Patients with lichen sclerosus were significantly older than those who presented with any of the other diseases. No differences were found in terms of either the time of disease evolution or in symptom presentation.

STUDY LIMITATIONS

Retrospective study. Vulvar diseases with an infectious cause are usually managed in primary care, therefore, were not included. All patients were recruited from a single private hospital which limits the comparisons with the public health system.

CONCLUSIONS

Vulvar diseases frequently occur and are associated with high morbidity. It is essential to promote the development of specific vulvar consultations in hospitals. Specialties such as dermatology, gynecology, urology, or physiotherapy must be part of these units.

摘要

背景

外阴疾病在普通人群中较为常见,对生活质量有负面影响。

目的

描述皮肤科医生在处理外阴皮肤病咨询方面的经验。

方法

对 5 年内参加专题外阴咨询的患者进行回顾性观察性研究。从患者病历中获取临床信息。

结果

共研究了 148 名女性。她们的平均年龄为 43.24 岁(标准差:15.15 岁),年龄范围为 4 个月至 80 岁。53.4%的患者首次就诊需要 2 至 5 年的时间。最常见的诊断是硬化性苔藓(41.9%)、外阴刺激性湿疹(14.9%)和慢性单纯性外阴苔藓(10.1%)。83.8%的患者报告有肛门生殖器瘙痒,66.2%有疼痛,45.9%有性交困难。最常开的处方是超强效外用皮质类固醇(丙酸氯倍他索;41.2%)。患有硬化性苔藓的患者明显比患有其他任何疾病的患者年龄更大。在疾病演变时间或症状表现方面没有差异。

研究局限性

回顾性研究。具有感染性病因的外阴疾病通常在初级保健机构管理,因此未包括在内。所有患者均来自于一家私立医院,这限制了与公共卫生系统的比较。

结论

外阴疾病经常发生,且发病率较高。在医院中推广专门的外阴咨询非常重要。皮肤科、妇科、泌尿科或理疗科等专业科室必须成为这些单位的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/b1203b2dfd00/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/bead1b422a11/gr1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/c5d8f06bc37c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/b1203b2dfd00/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/bead1b422a11/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/8d2ac09ad60d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/c5d8f06bc37c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86a/9582872/b1203b2dfd00/gr4.jpg

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本文引用的文献

1
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J Am Acad Dermatol. 2020 Jun;82(6):1277-1284. doi: 10.1016/j.jaad.2019.07.115. Epub 2019 Nov 8.
2
Vulvar diseases: Conditions in adults and children.外阴疾病:成人和儿童的病症。
J Am Acad Dermatol. 2020 Jun;82(6):1287-1298. doi: 10.1016/j.jaad.2019.10.077. Epub 2019 Nov 8.
3
Provoked vulvar vestibulodynia: Epidemiology in Europe, physio-pathology, consensus for first-line treatment and evaluation of second-line treatments.诱发性外阴前庭炎:欧洲的流行病学、生理病理学、一线治疗共识及二线治疗评估
外阴硬化性苔藓:探索性激素动态变化与开创个性化治疗模式
J Pers Med. 2024 Jan 8;14(1):76. doi: 10.3390/jpm14010076.
J Gynecol Obstet Hum Reprod. 2019 Oct;48(8):685-688. doi: 10.1016/j.jogoh.2019.04.011. Epub 2019 Apr 30.
4
Clinical and epidemiological profile of patients attended in a vulvar clinic of the dermatology outpatient unit of a tertiary hospital during a 4-year period.4 年期间皮肤科门诊外阴诊所就诊患者的临床和流行病学特征。
Int J Dermatol. 2019 Nov;58(11):1311-1316. doi: 10.1111/ijd.14442. Epub 2019 Mar 20.
5
Diagnosis and Treatment of Vulvar Lichen Sclerosus: An Update for Dermatologists.外阴硬化性苔藓的诊断与治疗:皮肤科医生的最新观点。
Am J Clin Dermatol. 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7.
6
Systematic review of pelvic floor interventions during pregnancy.系统评价妊娠期间盆底干预措施。
Int J Gynaecol Obstet. 2018 Oct;143(1):10-18. doi: 10.1002/ijgo.12513. Epub 2018 May 18.
7
British Association of Dermatologists guidelines for the management of lichen sclerosus, 2018.英国皮肤科医师协会2018年扁平苔藓硬化症管理指南
Br J Dermatol. 2018 Apr;178(4):839-853. doi: 10.1111/bjd.16241.
8
Pelvic Floor Physical Therapy for Vulvodynia: A Clinician's Guide.女性外阴痛的盆底物理治疗:临床医生指南。
Obstet Gynecol Clin North Am. 2017 Sep;44(3):509-522. doi: 10.1016/j.ogc.2017.05.006.
9
2016 European guideline for the management of vulval conditions.《2016年欧洲外阴疾病管理指南》
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10
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